基于国家免费孕前检查的不同年龄段女性检查方案的优化  

Optimization of pre-pregnancy examination programs for women of different ages based on national free pre-pregnancy examination

作　　者：淡堰璇 刘崇东[2] DAN Yanxuan;LIU Chongdong(Women’s Health Center,Maternal and Child Health Care Hospital of Xicheng District in Beijing,Beijing 100054,China;Department of Obstetrics and Gynecology,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China)

机构地区：[1]北京市西城区妇幼保健院妇女保健中心,北京100054 [2]首都医科大学附属北京朝阳医院妇产科,北京100020

出　　处：《妇儿健康导刊》2023年第5期56-60,共5页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

摘　　要：目的探讨基于国家免费孕前优生健康检查的不同年龄段女性检查方案的优化。方法选取2021年1月至12月在北京市西城区妇幼保健院进行免费孕前检查的800名备孕女性作为研究对象,采用随机数字表法分为实验组与观察组,每组各400名。其中实验组高龄段100名(年龄≥35岁)、适龄段300名(年龄<35岁)。观察组高龄段100名(年龄≥35岁)、适龄段300名(年龄<35岁)。观察组仅接受免费孕前检查;实验组适龄段在免费孕前检查基础上增加游离甲状腺素及抗甲状腺过氧化物酶抗体检测,实验组高龄段在免费孕前检查基础上增加抗米勒管激素、糖化血红蛋白检测。比较两组甲状腺功能与血糖状态,比较适龄段与高龄段促甲状腺激素与空腹血糖异常情况及实验组高龄段的卵巢储备功能减退检出情况。结果适龄段的促甲状腺激素异常检出率高于高龄段,高龄段的空腹血糖检出率高于适龄段,差异有统计学意义(P<0.05);实验组适龄段的甲状腺功能异常检出率高于观察组适龄段,实验组高龄段的血糖异常检出率高于观察组高龄段(P<0.05);实验组高龄段检出卵巢储备功能减退28例(28%)。结论针对不同年龄段女性,在现有免费孕前优生健康检查基础上增加相关检查,能提升甲状腺功能、血糖异常检出率,根据检查结果及时进行干预,进而缩短妊娠等待时机,对改善备孕女性健康有积极意义。Objective To explore the optimization of the examination program for women of different ages based on the national free pre-pregnancy examination.Methods A total of 800 pregnant women who received free prepregnancy examination in Maternal and Child Health Care Hospital of Xicheng District in Beijing from January to December 2021 were selected as research objects,and they were divided into experimental group and observation group by random number table method,with 400 cases in each group.There were 100 advanced age(≥35 years old)and 300 appropriate age(<35 years old)in the experimental group.In the observation group,there were 100 advanced age(≥35 years old)and 300 appropriate age(<35 years old).The observation group only received free pre-pregnancy examination.In the experimental group,free thyroxine and thyroid peroxidase antibody detection were added to the free pre-pregnancy examination in the appropriate age,and anti-Müllerian hormone and glycosylated hemoglobin detection were added to the free pre-pregnancy examination in the advanced age.The thyroid function and blood glucose status of the two groups were compared,and the abnormal thyroid stimulating hormone and fasting blood glucose of the appropriate age and the advanced age were compared.The detection of decreased ovarian reserve of the advanced age in the experimental group was compared.Results The abnormal detection rate of thyroid stimulating hormone in the appropriate age was higher than that in the elderly group,and the abnormal detection rate of fasting blood glucose in the advanced age was higher than that in the appropriate age,and the differences were statistically significant(P<0.05).The detection rate of abnormal thyroid function in the experimental group appropriate age was higher than that in the observation group appropriate age,and the detection rate of abnormal blood glucose in the experimental group advanced age was higher than that in the observation group advanced age(P<0.05).In the experimental group advanced age,28 cases(28%)wer

关 键 词：孕前保健 甲状腺功能 血糖异常 卵巢储备功能减退 

分 类 号：R173[医药卫生—妇幼卫生保健]