二乙氨基羟苯甲酰基苯甲酸己酯结晶速率的影响因素  

Influence factors of crystallization rate of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]-benzoate

作　　者：张倩洁 吕庆 张冬梅[1,2] 蒋汶 张婉萍[1,2] ZHANG Qianjie;LYU Qing;ZHANG Dongmei;JIANG Wen;ZHANG Wanping(College of Perfume and Aroma Technology,Shanghai Institute of Technology,Shanghai 201418,China;Engineering Research Center of Perfume&Aroma and Cosmetics,Ministry of Education,Shanghai 201418,China)

机构地区：[1]上海应用技术大学香料香精技术与工程学院,上海201418 [2]香料香精及化妆品教育部工程研究中心,上海201418

出　　处：《精细化工》2023年第2期337-342,共6页Fine Chemicals

摘　　要：考察了油脂种类、溶解方式、储存条件及乳化剂对当前使用最广泛的防晒剂二乙氨基羟苯甲酰基苯甲酸己酯(DHHB)的溶解度及结晶情况的影响。在肉豆蔻酸异丙酯(IPM)、辛酸/癸酸三甘油酯(318)、碳酸二乙基己酯(DEC)、C12-15醇苯甲酸酯(TN)、碳酸二辛酯(CC)、异壬酸异壬酯(ININ)、苯甲酸苯乙酯(226)7种油脂中,分子结构中含有苯环数目较多的226对DHHB的相容性最佳,超声溶解后25℃下放置28d时的溶解度为241.08 g/L;加热溶解25℃放置1~28 d时DHHB在各油脂中的溶解度下降率比超声溶解溶解度下降率降低10%以上,其中,在226中的溶解度下降率降低了35.72%;乳化剂的加入可明显减缓DHHB在CC中的溶解度下降率,其中,加入Span20后溶解度下降率降低了20.07%,加入Span80后溶解度下降率降低了21.27%。The effects of oil type,dissolution method,storage condition and emulsifier on the solubility and crystallization of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate(DHHB),the most widely used sunscreen agent,were investigated.Among the 7 types of fat:isopropyl myristate(IPM),caprylic/capric triglyceride(318),bis(2-ethylhexyl)carbonate(DEC),C12-15 alkyl benzoate(TN),carbonicacid,dioctylester(CC),isononyl isononanoate(ININ)and phenethyl benzoate(226),226 containing a large number of benzene rings in its molecular structure displayed the best compatibility for DHHB,showing a solubility of241.08 g/L when stored at 25℃for 28 d after ultrasonic dissolution.When DHHB was stored at 25℃for 1 d to 28 d after heated dissolution,the solubility decline rate in each oil decreased by more than 10%in comparison to that of ultrasonic dissolution,of which the solubility decline rate in 226 was reduced by35.72%.Moreover,the addition of emulsifier could significantly slow down the solubility decline rate of DHHB in dioctyl carbonate(CC),and the solubility decline rate reduced by 20.07%after Span20 addition while decreased by 21.27%with Span80 addition.

关 键 词：防晒剂 溶解度 超声溶解 加热溶解 乳化剂 结晶速率 日化原料 

分 类 号：TQ658.24[化学工程—精细化工]