烷基铝氧烷合成技术研究进展  

Research progress on synthesis of alkylaluminoxanes

作　　者：张梦波 楼琳瑾 冯艺荣 郑雨婷 张浩淼[1] 王靖岱[1] 阳永荣[1] ZHANG Mengbo;LOU Linjin;FENG Yirong;ZHENG Yuting;ZHANG Haomiao;WANG Jingdai;YANG Yongrong(State Key Laboratory of Chemical Engineering,College of Chemical and Biological Engineering,Zhejiang University,Hangzhou 310058,Zhejiang,China)

机构地区：[1]化学工程联合国家重点实验室,浙江大学化学工程与生物工程学院,浙江杭州310058

出　　处：《化工学报》2023年第2期525-534,共10页CIESC Journal

基　　金：国家自然科学基金项目(21908190);化学工程联合国家重点实验室课题项目(SKL-Ch E-19T05,SKL-Ch E-22D04)。

摘　　要：基于传统釜式反应器的烷基铝氧烷生产技术仍存在过程危险、控制难、收率低、经济性差等问题,首先回顾了传统烷基铝水解路线中将水以不同方式引入反应体系的过程,重点介绍了应用3D打印和流动化学技术的烷基铝氧烷合成系统设计,包括甲基铝氧烷(MAO)与异丁基铝氧烷(IBAO)合成、产物在线监测、反应焓测定以及改性甲基铝氧烷(MMAO)合成。流动化学系统将水以单分散微水滴的形式引入反应体系,提高了反应的传热、传质性能,实现了烷基铝氧烷的小型化、连续化、安全化生产,产品收率高,其助催化活性均达到或超过市售产品水平,并可通过微反应器放大技术进一步扩大生产能力。流动化学合成烷基铝氧烷的技术具有广阔应用前景,也为其他快速、强放热、多相反应提供了解决方案。The product of methylaluminoxane(MAO)is available commercially,however,central challenges over poor process control,low product yield,and high safety risks,still remain in its synthesis using large-scale reactors.This review presents several conventional hydrolytic routes for MAO synthesis with different techniques to supply water in the reaction system,and primarily focuses upon the development of continuous flow platforms to synthesize MAO,isobutylaluminoxane(IBAO),and modified methylaluminoxane(MMAO)using 3D printed functional devices.In particular,those flow platforms introduce monodisperse microdroplets of water to improve the heat and mass transfer,achieving inherently safe productions of alkylaluminoxanes with high yield and superior co-catalytic activity.The presented flow strategy has a wide array of applications in chemical synthesis,especially when handling fast,highly exothermic,multiphase reactions.

关 键 词：烷基铝氧烷 流动化学 3D打印 多相反应器 水解 合成 茂金属催化剂 

分 类 号：TQ31[化学工程—高聚物工业]