肺部感染患者药物治疗依从性调查分析及其影响因素的Logistic回归分析  

Investigation and Analysis of Medication Compliance in Patients with Pulmonary Infection and Logistic Regression Analysis

作　　者：邓娟 DENG Juan(Huangling Health Center,Minhe Town,Jinxian County,Jinxian 331700,China)

机构地区：[1]进贤县民和镇凰岭卫生院,江西进贤331700

出　　处：《中国医药指南》2023年第7期114-116,共3页Guide of China Medicine

摘　　要：目的探讨肺部感染患者药物治疗依从性调查分析及其影响因素的Logistic回归分析。方法选择2020年5月至2022年6月肺部感染患者178例为对象,所有患者均给予药物治疗,参考Morisky-Green标准及国内二相关评分标准设计调查表,根据调查结果分为治疗依从性好组(得分≥12分)和治疗依从差组(得分<12分)。查阅两组病历资料,对患者药物治疗依从性可能的影响因素进行单因素和多因素Logistic回归分析。结果178例肺部感染患者均完成药物依从性调查,37例患者治疗依从性差,占20.79%。单因素及多因素Logistic回归分析结果表明:病程(OR=3.582,95%CI=2.482~6.313)、服药时间(OR=6.413,95%CI=5.682~8.452)、用药种类(OR=4.083,95%CI=3.235~4.572)、药物不良反应(OR=1.034,95%CI=0.283~4.394)、健康教育(OR=1.246,95%CI=0.987~1.583)、用药指导(OR=1.632,95%CI=1.231~1.986)均是影响肺部感染患者药物治疗依从性的危险因素(P<0.05)。结论肺部感染患者药物治疗总体依从性良好,但受到多种主客观因素的影响,应采取相应的干预措施以提高治疗效果。Objective To explore the investigation and analysis of medication compliance in patients with pulmonary infection and the influence of multiple Logistic regression analysis.Methods A total of 178 patients with pulmonary infection from May 2020 to June 2022 were selected as subjects,all of which were given drug therapy.A questionnaire was developed based on Morisky-Green criteria and domestic 2 relevant scoring criteria.According to the survey results,the patients were divided into treatment compliance group(score≥12 points)and treatment non-adherence group(score<12 points).After consulting the medical records of the two groups,univariate and multivariate Logistic regression analysis were performed on the possible influencing factors of patients'medication compliance.Results All 178 patients with pulmonary infection completed the drug compliance survey,37 patients had poor treatment compliance,accounting for 20.79%.Univariate and multivariate Logistic regression analysis showed that:Duration of disease(OR=3.582,95%CI=2.482-6.313),duration of medication(OR=6.413,95%CI=5.682-8.452),type of medication(OR=4.083,95%CI=3.235-4.572),adverse drug reactions(OR=1.034,95%CI=0.283-4.394),health education(OR=1.246,95%CI=0.987-1.583),medication guidance(OR=1.632,95%CI=1.231-1.986)were risk factors for medication compliance in patients with pulmonary infection(P<0.05).Conclusion The overall compliance of patients with pulmonary infection is good,but it is affected by various subjective and objective factors.Corresponding intervention measures should be taken to improve the therapeutic effect.

关 键 词：肺部感染 药物治疗 依从性调查 多因素LOGISTIC回归分析 干预措施 治疗效果 

分 类 号：R563[医药卫生—呼吸系统]