中西医结合疗法治疗乙型肝炎肝硬化顽固性腹水患者的治疗效果分析  

Analyze the Therapeutic Effect of Integrated Traditional Chinese and Western Medicine in the Treatment of Patients with Hepatitis B Liver Cirrhosis and Refractory Ascites

作　　者：周磊 ZHOU Lei(Department of Gastroenterology,Panjin Central Hospital,Panjin 124000,China)

机构地区：[1]盘锦市中心医院消化科,辽宁盘锦124000

出　　处：《中国医药指南》2023年第7期130-132,共3页Guide of China Medicine

摘　　要：目的研究乙型肝炎肝硬化顽固性腹水患者采用中西医结合治疗的临床价值。方法研究时段是2018年1月至2019年5月,研究对象是我院接收的80例乙型肝炎肝硬化顽固性腹水患者,按照“用药差异性”随机分为观察组(中医学结合疗法)与对照组(西医疗法)各40例,比较两组肝功能、临床指标、治疗效果及不良反应。结果治疗前比较两组肝功能及临床指标无差异,P>0.05;治疗后与对照组比较,观察组ALT、AST、ALP指标更低,γ-GT指标更高;腹围更小、体质量更低、24 h尿量更多,差异有显著性(P<0.05);观察组治疗有效率(97.50%)高于对照组(85.00%),观察组不良反应发生率(5.00%)低于对照组(20.00%),差异有显著性(χ^(2)=3.914,4.114,P=0.048,0.043)P<0.05。结论中西医结合治疗乙型肝炎肝硬化顽固性腹水患者能提高整体疗效、改善肝功能,保证治疗有效性及安全性,避免不良反应的发生,利于改善预后效果、稳定病情。Objective To study the clinical value of combined traditional Chinese and western medicine in patients with refractory ascites due to hepatitis B liver cirrhosis.Method The study period is January 2018-May 2019 The research objects are 80 patients with hepatitis B cirrhosis and refractory ascites received in our hospital.According to the“drug difference”,they are randomly divided into observation group(integrated traditional Chinese medicine therapy)and control group(western medicine method).For 40 cases,the two groups compared liver function,clinical indicators,treatment effects and adverse reactions.Results There was no difference in liver function and clinical indicators between the two groups before treatment,P>0.05;after treatment,compared with the control group,the observation group had lower ALT,AST,ALP indicators,and higherγ-GT indicators;abdominal circumference was smaller and body weight Lower,more urine output in 24 hours;The observation group has lower AST and ALT values,smaller abdominal circumference,and more urine output in 24 hours;the observation group has a higher treatment efficiency(97.50%)than the control group(85.00%),and the observation group has a lower incidence of adverse reactions(5.00%)control group(20.00%),χ^(2)=3.914,4.114,P=0.048,0.043.Conclusion The combination of traditional Chinese and Western medicine in the treatment of patients with hepatitis B cirrhosis and refractory ascites can improve the overall efficacy,improve liver function,ensure the effectiveness and safety of the treatment,avoid side effects,improve the prognosis,and stabilize the disease.

关 键 词：乙型肝炎 肝硬化 顽固性腹水 中西医结合疗法 肝功能 治疗效果 

分 类 号：R459[医药卫生—治疗学]