河南地区高血压病人使用单片复方制剂的降压达标情况及影响因素  

Blood Pressure Control Status in Hypertensive Patients Treated by Single-pill Combination in Henan Province and Its Influencing Factors

作　　者：王锐 董化雷 李萌 段小凯 邱辉 王超 刘志力 吴红友 管海博 姜辉 宋丽娟 王永[10] 李利霞 邢青川 孙建军 李允[14] 杨青 王利民[16] 宋莎莎 谢高丽 马俊保 蔺志娟 尹宏磊[21] 王学珍[22] 金玉 WANG Rui;DONG Hualei;LI Meng;DUAN Xiaokai;QIU Hui;WANG Chao;LIU Zhili;WU Hongyou;GUAN Haibo;JIANG Hui;SONG Lijuan;WANG Yong;LI Lixia;XING Qingchuan;SUN Jianjun;LI Yun;YANG Qing;WANG Limin;SONG Shasha;XIE Gaoli;MA Junbao;LIN Zhijuan;YIN Honglei;WANG Xuezhen;JIN Yu(Henan Rongjun Hospital,Xinxiang 453000,Henan,China)

机构地区：[1]河南省荣军医院,河南新乡453000 [2]新乡医学院第五临床学院,河南新乡453000 [3]郑州市第一人民医院 [4]郑州颐和医院 [5]河南省胸科医院 [6]许昌市人民医院 [7]郑州大学第五附属医院 [8]郑州市第二人民医院 [9]郑州市第三人民医院 [10]焦作市人民医院 [11]沁阳市中医院 [12]中牟县人民医院 [13]新郑市人民医院 [14]安阳地区医院 [15]鹤壁市人民医院 [16]濮阳市中医院 [17]河南大学淮河医院 [18]杞县人民医院 [19]洛阳市中医院 [20]平顶山市第二人民医院 [21]新乡医学院第一附属医院 [22]商丘市第一人民医院

出　　处：《中西医结合心脑血管病杂志》2023年第5期889-894,共6页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：河南省科技发展计划项目(No.212102310836)。

摘　　要：目的:分析河南地区高血压病人使用单片复方制剂(SPC)的血压达标情况及影响因素。方法:在24所医院筛选血压大于140/90 mmHg的高血压病人,处方SPC,采用家庭自测血压,病人自行记录使用14 d时的血压控制情况,比较不同特征病人的血压达标差异,采用Logistics回归分析血压达标的影响因素。结果:纳入5132例病人,服用SPC后,病人血压开始逐渐下降,前5 d降幅最高,治疗第14天血压达标为45.6%。不同级别医院(χ^(2)=74.121,P<0.001)、不同用药剂量(χ^(2)=47.364,P<0.001)、有无高血压家族史(χ^(2)=12.360,P<0.001)、有无合并症(χ^(2)=4.699,P<0.001)、有无吸烟史(χ^(2)=6.058,P=0.014)病人血压达标率比较,差异均有统计学意义;收缩压基线、舒张压基线、三级甲等医院、合并症、高血压家族史、吸烟史均是血压达标率的影响因素(P<0.05)。结论:SPC应用可提高血压达标率,但受血压基线、合并症、高血压病史等因素影响。Objective:To analyze the blood pressure control status and influencing factors of hypertension patients using single-pill combination(SPC)in Henan province.Methods:Hypertensive patients with blood pressure greater than 140/90 mmHg were screened in 24 hospitals,SPC was prescribed,and home blood pressure was used to measure blood pressure.Blood pressure control status was recorded by patients themselves for 14 days.The differences in blood pressure control status among patients with different characteristics were compared.Influencing factors was analyzed by Logistics regression.Results:A total of 5132 patients were included.After taking SPC,the blood pressure of the patients began to gradually decrease,and the decrease was the highest in the first 5 days.The blood pressure target rate on the 14th day of treatment were 45.6%.There were statistically significant differences in blood pressure control rate among different levels of hospitals(χ^(2)=74.121,P<0.001),different drug doses(χ^(2)=47.364,P<0.001),different family history of hypertension(χ^(2)=12.360,P<0.001),different comorbidities(χ^(2)=4.699,P<0.001),and different smoking histories(χ^(2)=6.058,P=0.014).Baseline systolic blood pressure,baseline diastolic blood pressure,tertiary hospital,comorbidities,family history of hypertension,and smoking history were the influencing factors of blood pressure control rate(P<0.05).Conclusion:The application of SPC can improve the blood pressure target rate,but it is affected by factors such as blood pressure baseline,comorbidities,and history of hypertension.

关 键 词：高血压 河南地区 单片复方制剂 血压达标率 

分 类 号：R544.1[医药卫生—心血管疾病]