探究分化型甲状腺癌采取甲状腺全切除术治疗后的临床疗效  

Clinical Effect of Total Thyroidectomy for Differentiated Thyroid Carci⁃noma

作　　者：严建明[1] 储昭新 浦宸辰 YAN Jianming;CHU Zhaoxin;PU Chenchen(Department of Nail and Breast Surgery,Taicang First People´s Hospital,Taicang,Jiangsu Province,215400 China)

机构地区：[1]江苏省太仓市第一人民医院甲乳外科,江苏太仓215400

出　　处：《中外医疗》2022年第31期48-51,共4页China & Foreign Medical Treatment

基　　金：苏州市2018年度科技发展计划项目(SYSD2018039)。

摘　　要：目的 探讨分化型甲状腺癌采取甲状腺全切除术治疗后的临床疗效。方法 方便选取江苏省太仓市第一人民医院2016年6月—2019年12月收治的分化型甲状腺癌患者107例为研究对象,以随机数表法分为两组,对照组54例,观察组53例。对照组接受单侧甲状腺腺叶切除+峡部切除+患侧中央区淋巴结清扫术治疗,观察组接受双侧甲状腺全切除术+患侧中央区淋巴结清扫术治疗。比较两组治疗有效率、手术相关指标、并发症发生率与预后情况。结果 观察组治疗有效率(98.11%)高于对照组(81.48%),差异有统计学意义(χ^(2)=4.498,P<0.05);观察组手术时间为(102.35±20.98)min,长于对照组的(65.82±22.64)min,差异有统计学意义(t=8.653,P<0.05);观察组术中出血量为(30.65±8.77)mL,多于对照组的(21.63±6.52)mL,差异有统计学意义(t=6.045,P<0.05);观察组住院时间(7.85±1.69)d,长于对照组的(7.38±1.76)d,但差异无统计学意义(P>0.05)。观察组并发症发生率(47.17%)高于对照组(16.67%),差异有统计学意义(χ^(2)=11.480,P<0.05)。观察组局部复发率低于对照组(1.89%vs7.40%),但差异无统计学意义(χ^(2)=0.801,P>0.05);两组颈部淋巴结转移(5.56%vs1.89%)与远处转移率(3.70%vs0.00%)相比,差异无统计学意义(χ^(2)=0.241、0.491,P>0.05)。结论 双侧甲状腺全切除术治疗分化型甲状腺癌的疗效确切,可使患者的疾病预后得以改善,但会增加并发症的发生,术后需积极防治和处理。Objective To investigate the clinical effect of total thyroidectomy for differentiated thyroid carcinoma.Methods A total of 107 patients with differentiated thyroid cancer admitted to the Taicang First People´s Hospital from June 2016 to December 2019 were conveniently selected as the study subjects,which were divided into two groups by random number table method,54 in the control group and 53 in the observation group.The control group re⁃ceived unilateral thyroidectomy+isthmus resection+affected central lymph node dissection,and the observation group received bilateral total thyroidectomy+affected central lymph node dissection.The treatment efficiency,opera⁃tion related indexes,complication rate and prognosis were compared between the two groups.Results The effective rate of treatment in the observation group(98.11%)was higher than that in the control group(81.48%),and the differ⁃ence was statistically significant(χ^(2)=4.498,P<0.05);the operation time of observation group was(102.35±20.98)min,which was longer than that of control group(65.82±22.64)min,and the difference was statistically significant(t=8.653,P<0.05);the intraoperative blood loss in the observation group was(30.65±8.77)mL,which was higher than that in the control group(21.63±6.52)mL,and the difference was statistically significant(t=6.045,P<0.05);the length of stay in the observation group was(7.85±1.69)d,which was longer than that in the control group(7.38±1.76)d,but the difference was not statistically significant(P>0.05).The complication rate of the observation group(47.17%)was higher than that of the control group(16.67%),and the difference was statistically significant(χ^(2)=11.480,P<0.05).The local recurrence rate in the observation group was lower than that in the control group(1.89%vs7.40%),but the difference was not statistically significant(χ^(2)=0.801,P>0.05);there was no statistically significant difference in the rates of cervical lymph node metastasis(5.56%vs 1.89%)and distant metastasis(3.70%vs 0.00%)between the two

关 键 词：分化型甲状腺癌 甲状腺全切除术 低钙血症 并发症 喉返神经损伤 

分 类 号：R4[医药卫生—临床医学]