1,5-脱水葡萄糖醇在糖尿病中的临床研究进展  

Advances in Clinical Research of 1,5-anhydroglucitol in Diabetes Mellitus

作　　者：魏淑珍 吴婷[2] 张雨梅 WEI Shuzhen;WU Ting;ZHANG Yumei(Shazhou Community Health Service Center,Jianye District,Nanjing,Jiangsu Province,210000 China;ZhongdaHospital Affiliated to Southeast University,Nanjing,Jiangsu Province,210000 China)

机构地区：[1]南京市建邺区沙洲社区卫生服务中心,江苏南京210000 [2]东南大学附属中大医院,江苏南京210000

出　　处：《糖尿病新世界》2022年第24期193-198,共6页Diabetes New World Magazine

基　　金：南京市卫生科技发展专项资金资助项目(一般性课题)(YKK20186)。

摘　　要：作为一项非经典的短期血糖监测指标,血清1,5-脱水葡萄糖醇(1,5-anhydroglucitol, 1,5-AG)已经在临床研究中应用于糖尿病筛查、糖尿病管理、并发症管理及反映胰岛β细胞功能等方面。唾液1,5-AG作为无创血糖监测指标,已经开始探索并应用于糖尿病筛查及并发症管理方面。未来,还需要进行更快速、更准确的酶法检测唾液1,5-AG研究,以确定血清、唾液1,5-AG的正常参考值范围。此外,还需要加强大样本前瞻性临床研究,深入挖掘1,5-AG在糖尿病患者管理中的经济价值,从而更好地应用于患者的个体化诊疗。As a non classic short-term blood glucose monitoring indicator,serum 1,5-anhydroglucitol(1,5-AG)has been applied in clinical research for diabetes screening,diabetes management,complication management and islet re⁃flectionβcell function,etc.Saliva 1,5-AG,as a non-invasive blood glucose monitoring indicator,has begun to ex⁃plore and apply to diabetes screening and complication management.In the future,more rapid and accurate enzymatic detection of saliva 1,5-AG is needed to determine the normal reference value range of serum and saliva 1,5-AG.In addition,it is also necessary to strengthen the large sample prospective clinical research and deeply tap the economic value of 1,5-AG in the management of diabetes patients,so as to better apply it to the individualized diagnosis and treatment of patients.

关 键 词：1 5-脱水葡萄糖醇 糖尿病 血糖监测 

分 类 号：R587.1[医药卫生—内分泌]