结肠镜肠道准备质量受检者影响因素的Meta分析  

Individual factors influencing the colonoscopy bowel preparation quality:a Meta⁃analysis

作　　者：张娜 徐苗苗 张亚峰 王大毅[1] 冀静[1] 张旭红 ZHANG Na;XU Miaomiao;ZHANG Yafeng;WANG Dayi;JI Jing;ZHANG Xuhong(First Hospital of Shanxi Medical University,Shanxi 030001 China)

机构地区：[1]山西医科大学第一医院,山西030001 [2]武汉市中心医院

出　　处：《护理研究》2023年第6期963-969,共7页Chinese Nursing Research

基　　金：山西省卫生健康委科研项目,编号:2022016。

摘　　要：目的:系统评价结肠镜影响肠道准备质量的受检者因素。方法:计算机检索MedLine、EMbase、Web of Science、the Cochrane Library、ScienceDirect、中国生物医学文献数据库、中国知网、维普数据库及万方数据库中关于受检者因素对结肠镜肠道准备质量影响的研究,检索时限均为建库至2022年10月31日。由2名研究者根据纳入和排除标准独立筛选文献,并进行资料提取和质量评价。采用RevMan 5.4软件对纳入文献进行Meta分析。结果:共纳入22项研究。Meta分析结果显示:男性受检者肠道准备质量低于女性[OR=1.33,95%CI(1.16,1.53),P<0.0001],有慢性便秘的受检者肠道准备质量低于无慢性便秘的受检者[OR=3.20,95%CI(1.80,5.67),P<0.0001],合并糖尿病的受检者肠道准备质量低于无糖尿病的受检者[OR=4.72,95%CI(2.18,10.22),P<0.0001],使用阿片类药物的受检者肠道准备质量低于不使用阿片类药物的受检者[OR=1.60,95%CI(1.12,2.27),P=0.009],检查前高纤维饮食受检者肠道准备质量低于无高纤维饮食受检者[OR=2.94,95%CI(1.65,5.22),P=0.0003],检查前未完整服药受检者肠道准备质量低于完整服药受检者[OR=4.59,95%CI(3.45,6.10),P<0.0001],末次服药至检查时间间隔>5 h受检者肠道准备质量低于时间间隔在5 h之内的受检者[OR=2.82,95%CI(1.79,4.45),P<0.0001],末次排便非清水样便的受检者肠道准备质量低于末次排便为清水样便的受检者[OR=4.78,95%CI(2.35,9.71),P<0.0001]。结论:现有证据表明,男性、合并慢性便秘、合并糖尿病、使用阿片类药物、检查前高纤维饮食、未完整服药、末次服药至检查时间时隔>5 h、末次排便性状非清水样是影响结肠镜肠道准备质量的受检者因素。Objective:To systematically evaluate the individual factors of colonoscopy bowel preparation quality.Methods:Studies on influencing factors of colonoscopy bowel preparation quality were searched from PubMed,EMbase,Web of Science,the Cochrane Library,ScienceDirect,CBM,CNKI,VIP and WanFang Database.The retrieval time was from in ception to 31O ctober,2022.Two resea rchers independently screened the literature according to inclusion and exclusion criteria,and carried out quality evaluation and data extraction.RevMan 5.4 software was used for Meta⁃analysis.Results:A total of 22 studies were included.Meta-analysis results showed that:males had lower colonoscopy bowel preparation quality than females[OR=1.33,95%CI(1.16,1.53),P<0.0001],people with chronic constipation had lower colonoscopy bowel preparation quality than people without chronic constipation[OR=3.20,95%CI(1.80,5.67),P<0.0001],people with diabetes had lower colonoscopy bowel preparation quality than people without diabetes[OR=4.72,95%CI(2.18,10.22),P<0.0001],people taking opioids had lower colonoscopy bowel preparation quality than people not taking opioids[OR=1.60,95%CI(1.12,2.27),P=0.009],people intaking high⁃fiber meals had lower colonoscopy bowel preparation quality than people not taking high⁃fiber meals[OR=2.94,95%CI(1.65,5.22),P=0.0003],people failed to finish taking the laxative had lower colonoscopy bowel preparation quality than people completely taking the laxative[OR=4.59,95%CI(3.45,6.10),P<0.0001],people underwent colonoscopy with an interval time longer than five hours after finishing laxative had lower colonoscopy bowel preparation quality than people underwent colonoscopy within five hours[OR=2.82,95%CI(1.79,4.45),P<0.0001],people without clean⁃water⁃like last stool had lower colonoscopy bowel preparation quality than people with clean⁃water⁃like last stool[OR=4.78,95%CI(2.35,9.71),P<0.0001].Conclusions:Current evidence showed that male,with chronic constipation,with diabetes,opioids use,a high⁃fiber diet before examination,i

关 键 词：结肠镜检查 肠道准备质量 影响因素 META分析 循证护理 

分 类 号：R473[医药卫生—护理学]