hs-CRP及NT-proBNP对慢性心衰患者心衰程度及预后判断的价值  

Value of hs-CRP and NT-proBNP in Determining the Degree of Heart Failure and Prognosis in Patients with Chronic Heart Failure

作　　者：赵秋红 吕丽萍 鞠录升 ZHAO Qiuhong;LYU Liping;JU Lusheng(Department of Geriatrics II,Anqiu Traditional Chinese Hospital,Anqiu,Shandong Province,262100 China)

机构地区：[1]安丘市中医院老年病二科,山东安丘262100

出　　处：《系统医学》2022年第23期65-67,72,共4页Systems Medicine

摘　　要：目的分析hs-CRP及NT-proBNP对慢性心衰患者心衰程度及预后判断的价值。方法选取2020年1—12月在安丘市中医院接受治疗的25例患有慢性心衰的患者为观察组,选取同期来本院的25名健康体检者为对照组,检测对比两组患者hs-CRP及NT-proBNP水平,并分析其对慢性心衰患者心衰程度及预后判断的价值。结果观察组hs-CRP(20.18±3.68)mg/L、NT-proBNP(2569.21±479.29)pg/mL高于对照组的(4.57±1.13)mg/L、(196.37±47.51)pg/mL,差异有统计学意义(t=20.274、24.633,P<0.05);观察组随着心功能分级不断升高,hs-CRP及NT-proBNP水平也逐渐升高,差异有统计学意义(F=60.291、602.69,P<0.05);观察组患者中未发生心血管不良事件20例,发生心血管不良事件5例,其中发生心血管不良事件患者的hs-CRP及NT-proBNP水平均显著高于未发生心血管不良事件的患者,差异有统计学意义(t=2.219、2.222,P<0.05)。结论hs-CRP及NT-proBNP水平的升高对于评价慢性心衰患者的临床严重程度有着非常准确的判断,其临床价值较高,值得进一步推广并应用。Objective To analyze the value of hs-CRP and NT-proBNP in determining the degree of heart failure and prognosis in patients with chronic heart failure.Methods Selected 25 patients with chronic heart failure who were treated in Anqiu Hospital of Traditional Chinese Medicine from January to December 2020 as the observation group and selected 25 healthy people who came to our hospital during the same period as the control group,measured and compared the levels of hs-CRP and NT-proBNP in the two groups,and analyzed their value in judging the degree of heart failure and prognosis of patients with chronic heart failure.Results The hs-CRP(20.18±3.68)mg/L and the NT-proBNP(2569.21±479.29)pg/mL in the observation group was higher than tath of the control group(4.57±1.13)mg/L and(196.37±47.51)pg/mL,respectively,the difference was statistically significant(t=20.274,24.633,P<0.05);in the observation group,hs-CRP and NT-proBNP levels increased gradually with the continuous increase of cardiac func⁃tion classification,the difference was statistically significant(F=60.291,602.69,P<0.05);there were 20 patients with⁃out cardiovascular adverse events and 5 patients with cardiovascular adverse events in the observation group,in which the hs-CRP and NT-proBNP levels of patients with cardiovascular adverse events were significantly higher than those of patients without cardiovascular adverse events,the difference was statistically significant(t=2.219,2.222,P<0.05).Conclusion The elevation of hs-CRP and NT-proBNP levels is a very accurate judgment for evaluating the clinical severity of patients with chronic heart failure,and its clinical value is high,which is worth further promotion and appli⁃cation.

关 键 词：HS-CRP NT-PROBNP 慢性心衰 心衰程度 预后 

分 类 号：R541[医药卫生—心血管疾病]