不同冲洗液对慢性硬膜下血肿术后复发影响Meta分析  

EFFECT OF DIFFERENT IRRIGATION FLUIDS ON POSTOPERATIVE RECURRENCE OF CHRONIC SUBDURAL HEMATOMA:A META-ANALYSIS

作　　者：钟美香 徐璐璐 朱雨峰 杨玉媛 王萌[1] 郑雪平[1] ZHONG Meixiang;XU Lulu;ZHU Yufeng;YANG Yuyuan;WANG Meng;ZHENG Xueping(Department of Geriatric Medicine,The Affiliated Hospital of Qingdao University,Qingdao 266000,China)

机构地区：[1]青岛大学附属医院老年医学科,山东青岛266000 [2]青海大学研究生院

出　　处：《青岛大学学报（医学版）》2023年第1期60-63,共4页Journal of Qingdao University(Medical Sciences)

基　　金：国家自然科学基金青年科学基金项目(30901324)。

摘　　要：目的比较不同种类的冲洗液以及冲洗液温度对慢性硬膜下血肿(cSDH)颅骨钻孔冲洗引流术后复发的影响。方法检索PubMed、Embase、Cochrane Library、Web of science、CNKI、维普数据库,查找颅骨钻孔冲洗引流术治疗cSDH的研究,应用Meta方法分析不同种类的冲洗液以及冲洗液温度对cSDH颅骨钻孔冲洗引流术后复发的影响。结果共纳入9项研究2033例病人,其中有6项研究1175例病人涉及复发情况,3项研究858例病人涉及冲洗液温度对cSDH复发的影响。Meta分析显示,人工脑脊液组(n=576)术后复发率低于生理盐水组(n=599)(OR=0.41,95%CI=0.20~0.85,P=0.016),体温组(n=432)术后复发率明显低于室温组(n=426)(OR=2.92,95%CI=1.92~4.42,P<0.001)。结论cSDH颅骨钻孔冲洗引流术中,人工脑脊液体温冲洗能降低cSDH术后复发率。Objective To investigate the effect of different irrigation fluids and irrigation fluid temperature on the recurrence of chronic subdural hematoma(cSDH)after cranial drilling irrigation and drainage.Methods PubMed,Embase,the Cochrane Library,Web of science,CNKI,and VIP databases were searched for the studies of cranial drilling irrigation and drainage for the treatment of cSDH,and a Meta-analysis was performed to investigate the effect of different irrigation fluids and irrigation fluid temperature on the recurrence of cSDH after cranial drilling irrigation and drainage.Results A total of 9 studies were included,with 2033 patients in total,among whom 1175 patients from 6 studies had recurrence,and 858 patients from 3 studies involved the effect of irrigation fluid temperature on the recurrence of cSDH.The Meta-analysis showed that the artificial cerebrospinal fluid group with 576 patients had a significantly lower postoperative recurrence rate than the normal saline group with 599 patients(OR=0.41,95%CI=0.20-0.85,P=0.016),and the body temperature group with 432 patients had a significantly lower postoperative recurrence rate than the room temperature group with 426 patients(OR=2.92,95%CI=1.92-4.42,P<0.001).Conclusion In cranial drilling irrigation and drainage for cSDH,irrigation with artificial cerebrospinal fluid at body temperature can reduce the postoperative recurrence rate of cSDH.

关 键 词：血肿 硬膜下 灌洗疗法 引流术 人工脑脊液 META分析 

分 类 号：R651.15[医药卫生—外科学]