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作 者:徐金凤[1] 魏辰鸿 汪毅明 杨建波[1] 魏建刚[1] 张倩[1] 林晓静[1] 张小宁[1] XU Jin-feng;WEI Chen-hong;WANG Yi-ming;YANG Jian-bo;WEI Jian-gang;ZHANG Qian;Lin Xiao-jing;ZHANG Xiao-ning(The Second Department of Encephalopathy,the Affiliated Hospital of Traditional Chinese Medicine,Xinjiang Medical University,Urumqi 830001,China)
机构地区:[1]新疆医科大学附属中医医院脑病二科,乌鲁木齐830001
出 处:《中国临床神经科学》2023年第1期43-48,共6页Chinese Journal of Clinical Neurosciences
基 金:新疆医科大学科研创新基金项目(编号:ZYY201922)。
摘 要:目的探讨前庭康复训练法治疗中重度持续性姿势-感知性头晕(PPPD)的临床疗效分析。方法连续收集2020年9月至2021年12月脑病科门诊及病房确诊的60例中重度PPPD患者为研究对象。入选的研究对象均接受口服倍他司汀治疗。采用随机数字法将研究对象随机分为单用药物组(30例,倍他司汀)和联合干预组(30例,倍他司汀与前庭康复训练联合治疗)。盲法评估比较两组干预前和干预后的眩晕障碍量表(DHI)、前庭症状指数(VSI)评分结果。结果干预2周时,单用药物组与联合干预组比较,差异无统计学意义(P>0.05)。干预4周后,联合干预组DHI评分显著低于单用药物组,且联合干预组VSI评分明显低于单用药物组,组间比较差异均有统计学意义(均P<0.05)。干预8周后,联合干预组DHI评分显著低于单用药物组,且联合干预组VSI评分显著低于单用药物组,差异均有统计学意义(均P<0.05)。结论对中重度PPPD患者口服倍他司汀与前庭康复训练联合治疗较单用倍他司汀治疗,可以显著改善患者的眩晕及平衡障碍,有利于患者重新获得日常生活的独立性。Aim To investigate the clinical effect of vestibular rehabilitation training on moderate to severe persistent postural perceptual dizziness(PPPD).Methods From September 2020 to December2021,60 patients with moderate to severe PPPD diagnosed in the outpatient department and wards of the department of encephalopathy were collected as the research objects.All subjects were treated with oral betahistine.The subjects were randomly divided into a simple drug group(30 cases,oral betahistine group)and a combined intervention group(30 cases,oral betahistine treatment combined with vestibular rehabilitation training)by random number method.The vertigo scale(DHI)and vestibular symptom index(VSI)before and after intervention were evaluated and compared by blind method.Results After2 weeks of the intervention,there was no significant difference between the simple drug group and the combined intervention group(P>0.05).After 4 weeks of the intervention,the DHI score of the combined intervention group was significantly lower than that of the simple drug group,and the VSI score of the combined intervention group was significantly lower than that of the simple drug group,there was significant differences between the two groups(all P<0.05).After 8 weeks of the intervention,the DHI score of the combined intervention group was significantly lower than that of the simple drug group,and the VSI score of the combined intervention group was significantly lower than that of the simple drug group,there was significant differences(all P<0.05).Conclusion Use of vestibular rehabilitation training combined with oral betahistine in the treatment of moderate to severe persistent postural perceptual dizziness can significantly improve the dizziness and balance disorder of patients compared with oral betahistine alone,which is conducive to regaining the independence of daily life of patients.
关 键 词:前庭康复训练 持续性姿势-感知性头晕 眩晕障碍量表 前庭症状指数
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