补肾壮骨法联合碳酸钙对糖皮质激素性骨质疏松患者中医征候及骨密度的影响  

Effect of tonifying the kidney and strengthening the bone method combined with calcium carbonate on TCM symptoms and bone mineral density in patients with glucocorticoid-induced osteoporosis

作　　者：贺英[1] 黄觅[1] HE Ying;HUANG Mi(Orthopedics Department,Wuhan No.1 Hospital/Wuhan Hospital of Traditional Chinese&Western Medicine,Wuhan 430022)

机构地区：[1]武汉市第一医院/武汉市中西医结合医院骨科,湖北武汉430022

出　　处：《湖北中医药大学学报》2023年第1期101-103,共3页Journal of Hubei University of Chinese Medicine

基　　金：湖北省自然科学基金项目(项目编号:2018CFB695)。

摘　　要：目的观察补肾壮骨法联合碳酸钙对糖皮质激素性骨质疏松(GIOP)患者中医征候和骨密度的影响。方法将我院100例GIOP患者随机分成观察组与对照组各50例。对照组患者采用碳酸钙治疗。观察组患者采用补肾壮骨法、碳酸钙联合治疗。比较两组疗效,治疗前后两组中医证候积分、第1~4腰椎、左侧股骨颈、粗隆间、大转子、Ward’s三角骨密度。结果治疗后,观察组患者总有效率高于对照组(P<0.05);两组患者腰脊疼痛、腰膝酸软、脊背叩痛、下肢痿软、不能持重、眩晕耳鸣积分降低,观察组患者腰脊疼痛、腰膝酸软、脊背叩痛、下肢痿软、不能持重、眩晕耳鸣积分低于对照组(P<0.05);两组患者第1~4腰椎、左侧股骨颈、粗隆间、大转子、Ward’s三角骨密度增高;观察组患者第1~4腰椎、左侧股骨颈、粗隆间、大转子、Ward’s三角骨密度高于对照组(P<0.05)。结论补肾壮骨法联合碳酸钙对GIOP患者疗效明显,能显著改善中医征候,提高骨密度。Objective To observe the effect of tonifying the kidney and strengthening the bone method combined with calcium carbonate on TCM symptoms and bone mineral density in patients with glucocorticoid-induced osteoporosis(GIOP).Methods A total of 100 GIOP patients randomly divided into observation group and control group,with 50 cases in each group.Control group was treated with calcium carbonate,observation group was treated with tonifying the kidney and strengthening the bone method on the basis of control group.The curative effects of the two groups were compared,and the TCM syndrome scores,the 1~4 lumbar vertebras,the left femoral neck,the intertrochanter,the greater trochanter,and the Ward’s triangle bone mineral density were compared between the two groups before and after treatment.Results The total effective rate of observation group was higher than control group(P<0.05);lower back pain,soreness and weakness of the waist and knees,back percussion pain,atrophy and weakness of the lower extremities,inability to hold weight,dizziness and tinnitus scores decreased in both groups,and were lower in observation group than control group(P<0.05);the BMD of the 1~4 lumbar vertebras,left femoral neck,intertrochanteric,greater trochanter,and Ward’s triangle bene mineral density increased in both groups,and were higher in observation group than control group(P<0.05).Conclusion Tonifying the kidney and strengthening the bone method combined with calcium carbonate,which can significantly improve TCM symptoms and increase bone mineral density has obvious curative effect on patients with GIOP.

关 键 词：骨质疏松 糖皮质激素 骨密度 中医征候 补肾壮骨法 碳酸钙 

分 类 号：R259[医药卫生—中西医结合]