感染坏死性胰腺炎外科治疗现状和展望  

Current status and future prospect of surgical treatment of infected necrotizing pancreatitis

作　　者：肖枭 陈钱 梁荣 唐文链 汪伟民[1] 苗春木[1] 王运兵[1] 丁雄[1] XIAO Xiao;CHEN Qian;LIANG Rong;TANG Wen-lian;WANG Wei-min;MIAO Chun-mu;WANG Yun-bing;DING Xiong(Department of Hepatobiliary Surgery,Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)

机构地区：[1]重庆医科大学附属第二医院肝胆外科,重庆400010

出　　处：《局解手术学杂志》2023年第3期271-274,共4页Journal of Regional Anatomy and Operative Surgery

基　　金：重庆市自然科学基金面上项目(cstc2021jcyj-msxmX0294);重庆市自然科学基金博士后项目(cstc2020jcyj-bshX0033);重庆市科卫联合项目(2021MSXM139)。

摘　　要：急性胰腺炎是指因胰酶异常激活对胰腺自身及周围器官产生消化作用而引起的急腹症。急性胰腺炎发病率较高,并呈逐年上升趋势。感染坏死性胰腺炎(INP)是急性胰腺炎最严重的并发症,病死率高,其外科介入主要包括经皮穿刺引流术、微创手术、内镜治疗和开放手术等。本文综述了目前INP外科治疗的现状,并对其未来的治疗方向进行了展望,以期为临床INP治疗方法的选择提供理论依据。Acute pancreatitis is characterized as an acute abdominal condition caused by the aberrant activation of pancreatic enzymes,leading to autodigestion of the pancreatic parenchyma and surrounding tissues.The prevalence of acute pancreatitis is significant and displays a rising trend annually.Infected necrotizing pancreatitis(INP)is the most severe complication of acute pancreatitis with a high mortality rate,its surgical treatment encompasses percutaneous drainage,minimally invasive surgery,endoscopic therapy,and open pancreatic necrosectomy.This article offers a review of the contemporary state of surgical intervention of INP and outlines the potential therapeutic direction for future research in this field,thus providing a theoretical basis for the clinical decision-making regarding the therapeutic approaches of INP.

关 键 词：急性胰腺炎 感染坏死性胰腺炎 外科治疗 经皮穿刺引流术 微创手术 内镜治疗 阶梯治疗 展望 

分 类 号：R657.51[医药卫生—外科学]