基于固肾育胎生态疗法的精神疗法对气郁质PCOS不孕患者的研究  

Gushen Yutai ecological therapy combined with psychotherapy for infertile patients with qi-depression constitution PCOS

作　　者：彭少芳 单海萍 林锋敏 黄启祥[1] 吴佩莼[1] 蒋会芹[1] 卢沛金 陈协欣 马晓恩 Peng Shaofang;Shan Haiping;Lin Fengmin;Huang Qixiang;Wu Peichun;Jiang Huiqin;Lu Peijin;Chen Xiexin;Ma Xiao'en(Department of Gynecology of Traditional Chinese Medicine,Shantou Central Hospital,Shantou 515031,China)

机构地区：[1]汕头市中心医院中医妇科,汕头515031

出　　处：《国际医药卫生导报》2023年第6期781-785,共5页International Medicine and Health Guidance News

基　　金：广东省中医药局科研项目(20211363)。

摘　　要：目的探讨基于固肾育胎生态疗法的精神疗法对气郁质多囊卵巢综合征(PCOS)不孕患者的疗效、妊娠率、体质、焦虑状态、性激素水平[卵泡生成激素(FSH)、黄体生成激素(LH)、雌二醇(E2)、睾酮(T)、催乳激素(PRL)]的影响。方法采用试验研究,选取2021年1月至2022年6月就诊于汕头市中心医院和汕头市中心医院康复分院中医妇科,符合纳入标准的128例气郁质PCOS不孕患者,按照随机对照分组原则平均分为A、B、C、D组。A组32例,年龄24~36岁,采用常规疗法;B组32例,年龄23~40岁,采用固肾育胎生态疗法+常规疗法;C组32例,年龄25~38岁,采用固肾育胎生态疗法+常规疗法+精神疏导疗法;D组32例,年龄25~42岁,采用固肾育胎生态疗法+常规疗法+精神疏导疗法+四季音乐助孕疗法。以1个月经周期为1个疗程,治疗3个疗程后,比较4组的临床妊娠情况和治疗前后中医体质分类与判定自测表(CCMQ)气郁质评分、焦虑自评量表(SAS)评分、基础性激素水平。采用χ^(2)检验、方差分析进行统计分析。结果A组临床妊娠率为28.13%(9/32),B组为53.13%(17/32),C组为56.25%(18/32),D组为58.38%(19/32),B、C、D组与A组比较,差异均有统计学意义(均P<0.05)。CCMQ气郁质评分和SAS评分结果:C组、D组与治疗前比较改善明显,差异均有统计学意义(均P<0.05);D组治疗后与A、B组同期比较,差异均有统计学意义(均P<0.05)。A组总有效率为50.00%(16/32),B组为90.63%(29/32),C组为90.63%(29/32),D组为93.75%(30/32),B、C、D组与A组比较,差异均有统计学意义(均P<0.05)。治疗后,D组的LH和PRL水平较A组明显改善,差异均有统计学意义(均P<0.05)。结论基于固肾育胎生态疗法的精神疗法联合常规疗法可有效改善气郁质PCOS不孕患者的焦虑情绪,改善体质,调节性激素水平,提高妊娠率。Objective To investigate the effect of Gushen Yutai ecological therapy combined with psychotherapy on the efficacy,pregnancy rate,constitution,anxiety state,and sex hormones[follicle-stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E2),testosterone(T),and prolactin(PRL)]of infertile patients with qi-depression constitution polycystic ovarian syndrome(PCOS).Methods From January 2021 to June 2022,128 infertile patients with qi-depression constitution PCOS who were treated in Shantou Central Hospital and Department of Gynecology of Traditional Chinese Medicine (TCM), Rehabilitation Branch, Shantou Central Hospitaland who met the inclusion criteria were selected. They were divided into group A who were 24-36years old, group B who were 23-40 years old, group C who were 25-38 years old, and group D whowere 25-42 years old according to the principle of randomized control, with 32 cases in each group.Group A took routine therapy. Group B took Gushen Yutai ecological therapy and routine therapy.Group C took Gushen Yutai ecological therapy, routine therapy, and mental therapy. Group D tookGushen Yutai ecological therapy, routine therapy, mental therapy, and four-season music assistedpregnancy therapy. One menstrual cycle was taken as a treatment course. After three treatmentcourses, the clinical pregnancy conditions, TCM constitution classifications, scores of determinationself-test scale (CCMQ) qi-depression constitution and Self-Rating Anxiety Scale (SAS), and basic sexhormone levels before and after the treatment in the four groups were compared. χ^(2) test and analysisof variance were applied. Results The clinical pregnancy rates of group A, B, C, and D were 28.13%(9/32), 53.13% (17/32), 56.25% (18/32), and 58.38% (19/32), respectively, with statisticaldifferences between group B, C, and D and group A (all P<0.05). The scores of CCMQ qi-depressionconstitution and SAS in group C and D were significantly better as compared with those before thetreatment, with statistical differences (all P<0.05);the scores in

关 键 词：多囊卵巢综合征 固肾育胎生态疗法 精神疗法 气郁质 不孕 

分 类 号：R711.6[医药卫生—妇产科学]