超声引导下介入治疗卵巢子宫内膜异位症的效果及术后复发情况  

Effect and Recurrence of Ultrasound-Guided Interventional Treatment of Ovarian Endometriosis

作　　者：廉通 李爱芹 邹雁君 LIAN Tong;LI Aiqin;ZOU Yanjun(Department of Ultrasound,Nanyang Zhangzhongjing Hospital,Nanyang 473000,China)

机构地区：[1]南阳张仲景医院超声科,河南南阳473000

出　　处：《河南医学研究》2023年第4期706-709,共4页Henan Medical Research

摘　　要：目的 探究超声引导下介入治疗卵巢子宫内膜异位症患者的效果及复发情况。方法 选取南阳张仲景医院2020年6月至2021年6月收治的60例卵巢子宫内膜异位症患者作为研究对象,按照随机数字表法将其分为观察和对照两组,每组30例。对照组接受腹腔镜下卵巢子宫内腹异位症手术治疗,观察组接受超声引导下介入治疗。对比两组患者治疗前后的血清转录因子活化蛋白激酶B(JUNB)、糖类抗原125(CA125)、白细胞介素-6(IL-6)、雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)水平变化,以及对两组患者复发情况和并发症发生率进行比较。结果 治疗3个月后观察组患者的治疗有效率高于对照组患者(P<0.05)。治疗前两组的血清JUNB、CA125、IL-6、E2、FSH、LH水平差异无统计学意义(P>0.05)。治疗3个月后两组患者的血清JUNB、CA125、IL-6、E2、FSH水平均较治疗前下降(P<0.05),且治疗后观察组患者的血清JUNB、CA125、IL-6、E2、FSH水平均低于对照组患者(P<0.05)。治疗后两组患者LH水平均上升(P<0.05),但治疗后观察组LH水平低于对照组(P<0.05)。观察组患者的复发率和并发症发生率低于对照组患者(P<0.05)。结论 超声引导下介入治疗相对于腹腔镜下卵巢子宫内膜异位症剥除术治疗卵巢子宫内膜异位症患者疗效显著,可改善卵巢功能,且复发率和并发症发生率低,对患者预后具有积极作用,值得在临床推广使用。Objective To explore the effect of ultrasound-guided interventional therapy on patients with ovarian endometriosis and recurrence condition.Methods A total of 60 patients with ovarian endometriosis admitted to Nanyang Zhangzhongjing Hospital from June 2020 to June 2021 were selected as the study subjects. They were divided into observation and control groups according to the random number table method, with 30 patients in each group. The control group received laparoscopic surgery for ovarian endometriosis, and the observation group received ultrasound-guided interventional therapy. The levels of serum transcription factor-activated protein kinase B(JUNB), carbohydrate antigen 125(CA125), interleukin-6(IL-6), estradiol(E2), follicle-stimulating hormone(FSH), luteinizing hormone(LH) were compared before and after treatment. The recurrence rate and complication rate of the two groups were compared.Results After 3 months of treatment, the effective rate of treatment in the observation group was higher than that in the control group(P<0.05). There was no significant difference in serum JUNB, CA125, IL-6, E2, FSH and LH levels between the two groups before treatment(P>0.05). After 3 months of treatment, the serum levels of JUNB, CA125, IL-6, E2and FSH in the two groups were decreased compared with those before treatment(P<0.05), and the serum levels of JUNB, CA125, IL-6, E2, FSH levels were lower than the control group(P<0.05). After treatment, the LH levels in both groups increased(P<0.05), but the LH levels in the observation group were lower than those in the control group after treatment(P<0.05). The recurrence rate and complication rate of the observation group were lower than those of the control group(P<0.05).Conclusion Ultrasound-guided interventional therapy is more effective than laparoscopic excision of ovarian endometriosis in the treatment of patients with ovarian endometriosis, which can improve ovarian function. It has a low incidence rate and complication rate, has a positive effect on the prognosis of

关 键 词：卵巢子宫内膜异位症 超声引导下介入 卵巢功能 复发 预后 

分 类 号：R445.1[医药卫生—影像医学与核医学]