血液灌流治疗野生菌中毒的效果分析  

Effect Analysis of Hemoperfusion in Treatment of Wild Mushroom Poisoning

作　　者：李丽华[1] Li Li-hua(Guizhou Aerospace Hospital,Zunyi 563000,Guizhou Province,China)

机构地区：[1]贵州航天医院,贵州遵义563000

出　　处：《中国社区医师》2023年第5期67-69,共3页Chinese Community Doctors

摘　　要：目的:探讨血液灌流治疗野生菌中毒的效果。方法:选取2021年7月—2022年7月贵州航天医院收治的36例野生菌中毒患者作为研究对象,根据随机数字表法分为观察组与对照组,各18例。对照组给予对症支持治疗,观察组给予血液灌流治疗,比较两组凝血功能及肝功能指标。结果:治疗前,两组高敏C反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)比较,差异无统计学意义(P>0.05);治疗后,观察组hs-CRP、TNF-α均低于对照组,差异有统计学意义(P<0.05)。治疗前,两组尿素氮(BUN)、肌酐(Cr)水平比较,差异无统计学意义(P>0.05);治疗后,观察组BUN、Cr水平低于对照组,差异有统计学意义(P=0.000)。治疗前,两组丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)水平比较,差异无统计学意义(P>0.05);治疗后,观察组ALT、AST水平均低于对照组,差异有统计学意义(P=0.000)。结论:血液灌流治疗野生菌中毒的效果显著,可改善患者凝血功能及肝功能。Objective:To investigate the effect of hemoperfusion in the treatment of wild mushroom poisoning.Methods:A total of 36 patients with wild mushroom poisoning admitted to Guizhou Aerospace Hospital from July 2021 to July 2022 were selected as the study subjects,and they were divided into observation group and control group according to random number table method,with 18 cases in each group.The control group was given symptomatic supportive treatment,and the observation group was given hemoperfusion therapy.The coagulation function and liver function indexes of the two groups were compared.Results:Before treatment,there was no significant difference between the two groups in high-sensitivity C-reactive protein(hs-CRP)and tumor necrosis factor-α(TNF-α)(P>0.05).After treatment,hs-CRP and TNF-αin the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Before treatment,there was no significant difference between the two groups in the levels of urea nitrogen(BUN)and creatinine(Cr)(P>0.05).After treatment,the levels of BUN and Cr in the observation group were lower than those in the control group,and the difference was statistically significant(P=0.000).Before treatment,there was no significant difference between the two groups in the levels of alanine aminotransferase(ALT)and aspartate aminotransferase(AST)(P>0.05).After treatment,the levels of ALT and AST in the observation group were lower than those in the control group,and the difference was statistically significant(P=0.000).Conclusion:The effect of hemoperfusion in the treatment of wild mushroom poisoning is remarkable.It can alleviate the patient's coagulation function and liver function.

关 键 词：野生菌中毒 血液灌流 凝血功能 肝功能 

分 类 号：R595.7[医药卫生—内科学]