从“阴阳不和”理论角度探讨肠癌的发病机制、病机演变及临床治疗  

Discussion on pathogenesis,pathogenesis evolution and clinical treatment of intestinal cancer from the perspective of“the disharmony of yin and yang”

作　　者：王栋 孔宪斌 李清波 李雯 李玉 孟静岩[2] WANG Dong;KONG Xianbin;LI Qingbo;LI Wen;LI Yu;MENG Jingyan(Graduate School,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;College of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)

机构地区：[1]天津中医药大学研究生院,天津301617 [2]天津中医药大学中医学院,天津301617

出　　处：《天津中医药》2023年第3期301-306,共6页Tianjin Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81973728,82274396);天津市自然科学基金项目(18JCZDJC36600);国家重点基础研究发展计划项目(973计划)(2010CB530401);国家重点基础研究发展计划项目(973计划)(2013CB531701)。

摘　　要：中医认为肝脾不调、脾胃不和、肝胃不和等脏腑不和及气血津液不和、寒热不调等均归属于“阴阳不和”,与肠癌的发生和发展密切相关。基于此,提出“阴阳不和”是肠癌的核心发病机制。肠癌各期病机变化各异,是虚、实及虚实夹杂的动态演变,而非本虚标实一言概之,但皆因“阴阳不和”所致。故肠癌的中医治则当以“和法”为主,和其不和,“和法”应贯彻肠癌各期临床治疗始终,使其达到阴平阳秘。因此,文章从“阴阳不和”理论角度出发,探讨肠癌的发病机制、病机演变及临床治疗,以期为肠癌的中医临床诊疗提供思路。Traditional Chinese medicine believes that the disharmony of liver and spleen,the disharmony of spleen and stomach,the disharmony of liver and stomach,etc.,as well as disharmony of qi,blood and body fluids,and discordance of cold and heat are all attributed to disharmony between yin and yang,and are closely related to the occurrence and development of colon cancer.Based on this,it is proposed that“the disharmony of yin and yang”is the core pathogenesis of bowel cancer.The pathogenesis of colorectal cancer varies in different stages,which is the dynamic evolution of deficiency,excess,and the mixture of deficiency and excess,rather than the deficiency in origin and excess in superficiality,but all of them are caused by the disharmony between yin and yang.Therefore,the treatment of intestinal cancer in traditional Chinese medicine should be based on the“harmony method”,and its discord.“Harmony method”should be carried out throughout the clinical treatment of intestinal cancer in all stages,to achieve the balance of yin and yang.Therefore,from the perspective of the“disharmony between yin and yang”theory,this paper discusses the pathogenesis,pathogenesis evolution,and clinical treatment of colorectal cancer,to provide ideas for the clinical diagnosis and treatment of colorectal cancer.

关 键 词：肠癌 阴阳不和 发病机制 病机演变 临床应用 

分 类 号：R753.3[医药卫生—皮肤病学与性病学]