妊娠晚期B族链球菌感染的高危因素分析  

Analysis of high risk factors of Group B streptococcus infection in the third trimester of pregnancy

作　　者：杜佳丽 Du Jiali(Department of Gynecology,Suqian Hospital of Nanjing Gulou Hospital Group/Suqian Hospital Affiliated to Xuzhou Medical University,Suqian 223800,China)

机构地区：[1]南京鼓楼医院集团宿迁医院/徐州医科大学附属宿迁医院妇科,江苏宿迁223800

出　　处：《实用妇科内分泌电子杂志》2022年第29期16-18,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的分析本院孕35~37周孕妇B族链球菌(GBS)感染状况及高危因素。方法选取就诊的孕35~37周且建围生期保健册、规范产检的孕妇共3791例,均行B族链球菌检测,其中阳性162例孕妇为观察组;另外随机抽取200例阴性孕妇为对照组,最终信息获取完整者330例(观察组152例,对照组178例)。分析孕35~37周GBS感染的高危因素。结果本院孕35~37周孕妇GBS定植率为4.27%。单因素方差分析结果显示妊娠期糖尿病、妊娠期阴道炎、IVF-ET术后妊娠、妊娠期高血压疾病、妊娠期甲状腺功能减退是孕35~37周孕妇GBS感染的高危因素(P<0.05)。多因素Logistic回归分析显示妊娠期糖尿病、妊娠期阴道炎、IVF-ET术后、妊娠期甲减是妊娠35~37周孕妇GBS感染的高危因素(P<0.05)。结论妊娠期糖尿病、妊娠期甲减以及IVF-ET术、妊娠期阴道炎是妊娠晚期GBS感染的高危因素,需重视以上因素孕妇GBS检测,或妊娠前尽量避免以上因素的发生。Objective The infection status and risk factors of Group B streptococcus(GBS)in pregnant women at 35 to 37 weeks of pregnancy were analyzed.Methods A total of 3791 pregnant women from 35 to 37 weeks gestation who had established perinatal health register and standardized birth examination were selected.All of them were tested for group B streptococcus,among which 162 pregnant women were positive.In addition,200 negative pregnant women were randomly selected as the control group,and 330 of them had complete information(152 in the observation group and 178 in the control group).The risk factors of GBS infection at 35 to 37 weeks of pregnancy were analyzed.Results The GBS colonization rate of pregnant women at 35 to 37 weeks was 4.27%.Univariate analysis of variance showed that gestational diabetes mellitus,gestational vaginitis,pregnancy after IVF-ET,gestational hypertension and gestational hypothyroidism were the risk factors for GBS infection in pregnant women at 35 to 37 weeks of gestation(P<0.05).Multivariate Logistic regression analysis showed that gestational diabetes mellitus,gestational vaginitis,IVF-ET postoperative and gestational hypothyroidism were the risk factors for GBS infection in pregnant women at 35 to 37 weeks of gestation(P<0.05).Conclusion Gestational diabetes mellitus,pregnant women with hypothyroidism,IVF-ET surgery and pregnancy vaginitis are high risk factors for GBS infection in the third trimester of pregnancy.It is necessary to pay attention to the detection of GBS in pregnant women with the above factors,or try to avoid the occurrence of the above factors before pregnancy.

关 键 词：妊娠晚期 GBS感染 高危因素 

分 类 号：R714.2[医药卫生—妇产科学]