基于Q[6]·HAuCl_(4)/AuNPs构建的无标记电化学传感体系对尸胺的检测  

A Label-Free Electrochemical Sensor Based on Q[6]·HAuCl_(4)/AuNPs for Cadaverine Detection

作　　者：范颖 王成艳 葛庆梅 丛航 FAN Ying;WANG Chengyan;GE Qingmei;CONG Hang(Enterprise Technology Center of Guizhou Province,Guizhou University,Guiyang 550025,China)

机构地区：[1]贵州大学贵州省企业技术中心,贵州贵阳550025

出　　处：《贵州大学学报（自然科学版）》2023年第2期42-46,81,共6页Journal of Guizhou University:Natural Sciences

基　　金：贵州省科技计划资助项目(20201Y028);贵州大学人才引进资助项目(201902)。

摘　　要：利用瓜环基金属有机框架Q[6]·HAuCl_(4)与Au纳米颗粒复合构建了一种电化学传感器GCE-AuNPs-Q[6]·HAuCl_(4)检测尸胺,其中,大环化合物六元瓜环主要用于对尸胺的选择性识别,HAuCl_(4)和Au纳米颗粒极大提高了DPV电化学响应信号。该电化学传感器与电解液中K_(3)[Fe(CN)_(6)]/K_(4)[Fe(CN)_(6)]氧化还原探针的综合应用,开发了一个新颖的无标记定量检测尸胺的电化学分析体系,具有稳定性、选择性和灵敏度高,抗干扰能力强等优势,在0.6~10μM线性范围内,检出限达到0.03μM。应用该体系对枸杞酒中尸胺的检测也具有良好的回收率,体现了其实际应用价值。An electrochemical sensor,GCE-AuNPs-Q[6]·HAuCl_(4),was constructed to detect cadaverine with cucurbit[n]uril-based metal-organic framework Q[6]·HAuCl_(4) and Au nanoparticles.Q[6] was used for selective recognition to cadaverine,while HAuCl_(4) and Au nanoparticles greatly improved the electrochemical signal in DPV.In the presence of K_(3)[Fe(CN)_(6)]/K_(4)[Fe(CN)_(6)] redox probe in the electrolyte,the electrochemical sensor was developed for a novel label-free quantitative detection of cadaverine electrochemical analysis system,which had the advantages of stability,selectivity,high sensitivity and strong anti-interference ability,with a detection limit of 0.03 μM in the linear range of 0.6~10 μM.The application of this system for the detection of cadaverine in wine also afforded good recoveries,exhibiting practical application value.

关 键 词：瓜环 尸胺 电化学传感器 无标记分析 

分 类 号：O657.1[理学—分析化学]