上海口岸出境人群水痘IgG抗体水平分析  

Analysis of varicella IgG antibody level in the exit population in Shanghai port

作　　者：周璇[1] 周启明[1] 张静 秦佳[1] ZHOU Xuan;ZHOU Qiming;ZHANG Jing;QIN Jia(Shanghai International Travel Healthcare Center,Shanghai 200335,China)

机构地区：[1]上海国际旅行卫生保健中心,上海200335

出　　处：《中国国境卫生检疫杂志》2023年第1期15-19,共5页Chinese Journal of Frontier Health and Quarantine

摘　　要：目的了解上海口岸出境人群的水痘Ig G抗体阳性率,分析阳性率与性别、年龄的关系,以及中国籍与外国籍人群抗体阳性率之间的差异,为上海口岸出境人群国际旅行前的健康指导提供依据。方法采集上海口岸健康体检或预防接种的出境人群的性别、年龄、国籍等信息,通过酶联免疫分析法(ELISA)检测血清水痘-带状疱疹病毒(VZV)Ig G抗体,采用SPSS 26.0统计软件进行数据分析。结果2016—2020年上海口岸接受VZV Ig G抗体检测的出境人员29 478人,VZV Ig G抗体阳性率为81.6%,中国籍和外国籍人群的阳性率分别为81.4%和87.2%,差异无统计学意义(χ^(2)=2.286,P=0.131)。中国籍人群中男性和女性VZV Ig G抗体阳性率分别为82.0%和81.8%(χ^(2)=0.192,P=0.661)。抗体阳性率在不同年份间差异有统计学意义(χ^(2)=10.641,P=0.031),2017年阳性率显著低于2020年(χ^(2)=7.252,P=0.007)。VZV Ig G抗体阳性率随着年龄增长而升高(χ^(2)=12.210,P=0.032),其中0~<13岁人群抗体阳性率最低(73.4%),≥30岁的人群最高(90.9%)。结论中国籍与外国籍人群VZV Ig G抗体阳性率存在差别,但差异无统计学意义;抗体阳性率随年龄增长有所升高。从旅行者健康角度出发,建议向无明确水痘免疫接种证据的出境人员提供VZV Ig G抗体监测,并帮助其完善两剂次水痘疫苗接种,尤其是13岁以下儿童。Objective To understand the positive rate of varicella antibody among the exit population in Shanghai,and to analyze the relationship between the positive rate and gender and age,as well as the difference of the positive rate of antibody between Chinese and foreigners,which provides a basis for the health guidance of exit people at Shanghai port before international travel.Methods The information of gender,age and nationality of the exit population who had taken physical examination or vaccination at Shanghai port were collected,and serum varicellazoster virus (VZV) Ig G antibody was detected by enzyme-linked immunoassay (ELISA).The data were analyzed with SPSS 26.0 statistical software.Results From 2016 to 2020,there were 29 478 exit people under the detection of VZV Ig G antibody at Shanghai port,the positive rate was 81.6%,Chinese and foreigners were 81.4%and 87.2%,respectively.The positive rate of VZV Ig G antibody in foreigners was not significantly different from that in Chinese(χ^(2)=2.286,P=0.131).The positive rate in male and female in the Chinese were 82.0%and 81.8%,respectively(χ^(2)=0.192,P=0.661).The positive rates were different in different years(χ^(2)=10.641,P=0.031),and in 2017 was significantly lower than that in 2020(χ^(2)=7.252,P=0.007).In addition,the positive rates of VZV Ig G antibody increased with age(χ^(2)=12.210,P=0.032).Among them,the positive rate of people aged 0-<13 was the lowest (73.4%),and that of the people aged 30 and over was the highest (90.9%).Conclusion There is no significant statistical difference in the positive rate of VZV Ig G antibody between Chinese and foreigners,and the positive rate increased with age.From the perspective of traveler’s health,VZV Ig G antibody evaluation is suggested to the exit population that did not have the proof of varicella vaccination,and helping them to complete 2 shots of varicella vaccine,especially children under 13 years old.

关 键 词：水痘-带状疱疹病毒 IGG抗体 出境人群 免疫接种 

分 类 号：R186[医药卫生—流行病学]