盐酸左西替利嗪口服液联合糠酸莫米松鼻喷雾剂治疗儿童鼻后滴漏综合征的临床疗效  

Clinical Efficacy of Levocetirizine Hydrochloride Oral Solution Combined with Mometasone Furoate Aqueous Nasal Spray in Treatment of Postnasal Drip Syndrome in Children

作　　者：刘绘 杨丽 彭蓬[2] 钟翠鸣[1] 田小华[1] Liu Hui;Yang Li;Peng Peng;Zhong Cui-ming;Tian Xiao-hua(Guangdong Agricultural Reclamation Center Hospital,Zhanjiang 524002,Guangdong Province,China;Zhanjiang Fourth People's Hospital,Zhanjiang 524008,Guangdong Province,China)

机构地区：[1]广东省农垦中心医院,广东湛江524002 [2]湛江市第四人民医院,广东湛江524008

出　　处：《中外医药研究》2022年第15期70-72,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

基　　金：盐酸左西替利嗪口服液联合糠酸莫米松鼻喷雾剂(内舒拿)治疗儿童鼻后滴漏综合征临床疗效观察(编号:2021B01200)。

摘　　要：目的:观察盐酸左西替利嗪口服液联合糠酸莫米松鼻喷雾剂治疗儿童鼻后滴漏综合征的临床疗效。方法:选取2021年5-12月广东省农垦中心医院收治的鼻后滴漏综合征患儿90例为观察对象,根据随机数字表法分为对照组和观察组,各45例。对照组给予盐酸左西替利嗪口服液治疗,观察组给予盐酸左西替利嗪口服液联合糠酸莫米松鼻喷雾剂治疗。比较两组患儿治疗效果、复发率。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。观察组咳嗽、咽喉异物感复发率及总复发率低于对照组,差异有统计学意义(P<0.05)。结论:盐酸左西替利嗪口服液与糠酸莫米松鼻喷雾剂联合治疗儿童鼻后滴漏综合征,能够有效提升疾病治疗效果,疾病复发率控制良好。Objective:To observe the clinical efficacy of levocetirizine hydrochloride oral solution combined with mometasone furoate aqueous nasal spray in the treatment of postnasal drip syndrome in children.Methods:Ninety cases of children with postnasal drip syndrome admitted to Guangdong Agricultural Reclamation Center Hospital from May to December 2021 were selected as observation subjects,and were divided into control group and observation group according to the random number table method,with forty-five cases in each groups.The control group was treated with levocetirizine hydrochloride oral solution,and the observation group was treated with levocetirizine hydrochloride oral solution combined with mometasone furoate aqueous nasal spray.The treatment effect and recurrence rate of children in the two groups were compared.Results:The total treatment effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).The recurrence rate of cough,the recurrence rate of foreign body sensation in the throat and the total recurrence rate of the observation group were lower than those of the control group,and the difference was statistically significant(P<0.05).Conclusion:The combination of levocetirizine hydrochloride oral solution and mometasone furoate aqueous nasal spray in the treatment of postnasal drip syndrome in children can effectively improve the disease treatment effect and the disease recurrence rate is well controlled.

关 键 词：盐酸左西替利嗪口服液 糠酸莫米松鼻喷雾剂 儿童鼻后滴漏综合征 

分 类 号：R28[医药卫生—中药学]