早期血清ALB水平检测对预测急性心肌梗死患者急性肾损伤的临床价值  

The Clinical Value of Early Serum ALB Level in Predicting Acute Renal Injury in Patients with Acute Myocardial Infarction

作　　者：秦建林 QIN Jianin(Department of Clinical Laboratory,Zhenping Second People's Hospital of Henan Province,Nanyang,Henan 474250,China)

机构地区：[1]河南省镇平县第二人民医院检验科,河南南阳474250

出　　处：《生物医学工程学进展》2023年第1期96-102,共7页Progress in Biomedical Engineering

摘　　要：目的 分析早期检测血清白蛋白(albumin,ALB)对急性心肌梗死患者急性肾损伤的预测价值。方法 纳入急性心肌梗死患者100例,其中有急性肾损伤患者48例,无急性肾损伤患者48例,探讨早期血清ALB对急性心肌梗死患者发生急性肾损伤的预测价值。结果 两组患者在性别、年龄和体质量指数上无统计学差异(P>0.05);有急性肾损伤患者的心率、收缩压、舒张压、尿量、白细胞、血糖、血肌酐水平更高,行冠状动脉支架治疗概率、左室射血分数、红细胞比容、ALB水平更低(P<0.05);多因素Logistic回归分析显示,肾损伤的危险因素包括ALB、白细胞计数和血肌酐(P<0.05);经校正混杂因素后,低ALB血症为肾损伤的危险因素(P<0.05)。结论 早期检测血清ALB水平,可对急性心肌梗死患者发生急性肾损伤的风险进行预测。Objective To analyze the value of early detection of albumin(ALB)in predicting acute kidney injury in patients with acute myocardial infarction(AMI).Methods A total of 100 patients with acute myocardial infarction(AMI)were enrolled,including 48 patients with acute kidney injury and 48 patients without acute kidney injury.The predictive value of early ALB on acute kidney injury in AMI patients was investigated.Results There were no significant differences in gender,age and body mass index(P>0.05).Patients with renal injury had higher heart rate,systolic blood pressure,diastolic blood pressure,urine volume,white blood cell,blood glucose and serum creatinine,and lower probability of coronary artery stenting,left ventricular ejection fraction,erythrocyte specific volume and ALB levels(P<0.05).Multivariate logistic regression analysis showed that the risk factors of renal injury included ALB,white blood cell count and serum creatinine(P<0.05).After adjusting for confounding factors,hypo ALB was a risk factor for renal injury(P<0.05).Conclusion Early detection of serum ALB level can predict the risk of acute kidney injury in patients with acute myocardial infarction.

关 键 词：白蛋白 急性心肌梗死 急性肾损伤 预测价值 

分 类 号：R446.111[医药卫生—诊断学]