功能神经影像技术与经颅磁刺激联用在神经康复中的研究进展  

Research progress of functional neuroimaging combined with transcranial magnetic stimulation in neurorehabilitation

作　　者：应颖[1] 马兴怡 李杰[1] 祁文俊 林维山 杨婧瑞 李铁 徐文东[1,2,3,4] Ying Ying;Ma Xingyi;Li Jie;Qi Wenjun;Lin Weishan;Yang Jingrui;Li Tie;Xu Wendong(Jing'an District Central Hospital,Fudan University,Shanghai 200040,China;Huashan Hospital,Fudan University,Shanghai 200040,China;National Clinical Research Center for Aging and Medicine,Huashan Hospital,Fudan University,Shanghai 200040,China;Smart Medical Auxiliary Appliance Engineering Research Center,Shanghai 200040,China)

机构地区：[1]复旦大学附属静安区中心医院,上海200040 [2]复旦大学附属华山医院,上海200040 [3]国家老年疾病临床医学研究中心(华山),上海200040 [4]上海市人工智能医疗辅助器具工程研究中心,上海200040

出　　处：《生物医学转化》2023年第1期24-29,92,共7页Biomedical transformation

基　　金：国家自然科学基金创新研究群体项目(82021002);国家自然科学基金青年基金项目(81801363);中国医学科学院临床研究基金培育项目(2021-I2M-C&T-B-100)。

摘　　要：功能性神经影像和神经调控技术的联合应用已成为一个令人兴奋的领域,这为多种疾病损伤后大脑重塑的多尺度探索提供了丰富的视觉数据,并为神经康复带来了新的机遇和挑战。本文主要介绍了三种功能性神经影像(EEG、fMRI、fNIRS)和神经调控技术(TMS)的组合,阐述了这些组合的重要性,并讨论了它们在神经康复中的应用价值。基于这些组合的脑机接口和神经假肢等尖端技术,有望对疾病后神经回路重建进行更深入的分析,并为神经康复提供更精确的方案。The combined application of functional neuroimages and neuroregulatory technologies has become a promising field.It provides rich visual data for multi-scale exploration of brain plasticity after central injury caused by various reasons,and brings new opportunity and challenge to neurorehabilitation.This article mainly introduces three combinations of functional neuroimages(EEG,fMRI,fNIRS)and neuroregulatory technology(TMS),expounds the significance of the combinations and discusses their application value in neurorehabilitation.The cutting-edge technologies such as brain-computer interfaces and neuroprosthetics based on the combinations are expected to conduct more deeply analysis of neural circuit reconstruction after central injury and provide more accurate treatment programs for neurorehabilitation.

关 键 词：功能神经影像 经颅磁刺激 神经康复 

分 类 号：R445[医药卫生—影像医学与核医学] R49[医药卫生—诊断学]