肥胖导致慢病机制假说  

Hypothesis of the mechanism of obesity leading to chronic disease

作　　者：赖敏 袁文臻[2] LAI Min;YUAN Wenzhen(First School of Clinical Medicine,Lanzhou University,Lanzhou 730099,China;Department of Oncological Surgery,First Hospital of Lanzhou University,Lanzhou 730013,China)

机构地区：[1]兰州大学第一临床医学院,甘肃兰州730099 [2]兰州大学第一医院肿瘤外科,甘肃兰州730013

出　　处：《空军军医大学学报》2023年第3期284-288,共5页Journal of Air Force Medical University

基　　金：甘肃省自然科学基金(18JR3RA343)。

摘　　要：随着社会的发展,肥胖越来越普遍,慢病的发生率也越来越高,给国家和民众带来沉重负担。慢病种类繁多,治疗方式各不相同,但慢病发生发展存在共性。在整合医学视角下,本文从医学的整体观出发,基于神经内分泌、能量代谢、炎症免疫反应等机制,提出肥胖导致慢病的机制假说,并在“治未病”的理念下,提出以肥胖干预为抓手,减少慢病的理论。With the development of society,obesity is becoming more and more common,and the incidence of chronic diseases is also increasing,which brings heavy burden to the country and the general public.There are many kinds of chronic diseases,and their treatment methods are different,but there are similarities in their occurrence and development.From the perspective of holistic integrative medicine,this paper proposed the hypothesis of the mechanism of obesity leading to chronic diseases based on neuroendocrine,energy metabolism,inflammatory immune response and other mechanisms,and put forward the theory of obesity intervention as the starting point to reduce chronic diseases under the concept of“preventing disease”.

关 键 词：慢病 肥胖 整合医学 

分 类 号：R589.2[医药卫生—内分泌]