正交试验优选六子明目颗粒提取工艺研究  

Study on Optimization of Liuzi Mingmu Granules Extraction Process by Orthogonal Experiment

作　　者：唐宇晴 刘姗姗 张复中 沈刚 谭庆刍 鄢贵 Tang Yuqing;Liu Shanshan;Zhang Fuzhong;Shen Gang;Tan Qingchu;Yan Gui(Chengdu Institute of Chinese Herbal Medicine,Chengdu 610000;College of Food and Bio Engineering,Chengdu University,Chengdu 610000,China)

机构地区：[1]成都市中草药研究所,四川成都610000 [2]成都大学食品与生物工程学院,四川成都610000

出　　处：《广东化工》2023年第5期58-60,116,共4页Guangdong Chemical Industry

基　　金：成都市医学科研课题(2021406)。

摘　　要：目的:优选六子明目颗粒的最佳提取工艺。方法:采用单因素实验和正交实验,以提取时间、提取次数、料液比为考察因素,以浸膏量、总黄酮、总多糖提取率为综合评价指标,优选最佳提取工艺。结果:根据单因素和正交实验结果,药材进行粉碎后,料液比1∶12、提取时间1 h、提取次数3次为最佳工艺。结论:该工艺稳定、重复性好、可行性高,适用于工业生产。Objective:To optimize the extraction process of Liuzi Mingmu granules.Methods:Single factor experiment and orthogonal experiment were used to optimize the optimal extraction process.The extraction time,extraction times and solid-liquid ratio were taken as factors,and the extract quantity,total flavonoids and total polysaccharide extraction rate were taken as comprehensive evaluation indexes.Results:According to the results of single factor and orthogonal experiment,the optimal conditions were solid-liquid ratio 1∶12,extraction time 1h and extraction times 3.Conclusion:The process is stable,repeatable and feasible,and is suitable for industrial production.

关 键 词：六子明目颗粒 正交试验 提取工艺 综合评分法 

分 类 号：TQ[化学工程]