早期微量喂养联合综合口腔运动干预对晚期早产儿生长发育及血清胃肠激素水平的影响  

Effect of early microfeeding combined with integrated oral exercise intervention on growth and serum gastrointestinal hormones in late preterm infants

作　　者：朱玉华 朱宏瑞[1] 尚春灵 Zhu Yuhua;Zhu Hongrui;Shang Chunling(Intensive Care Unit for Premature Infants,Henan Children's Hospital/Zhengzhou Children's Hospital,Zhengzhou 450000,China)

机构地区：[1]河南省儿童医院郑州市儿童医院早产儿重症监护室,郑州450000

出　　处：《保健医学研究与实践》2023年第1期140-143,共4页Health Medicine Research and Practice

摘　　要：目的探讨早期微量喂养联合综合口腔运动干预对晚期早产儿生长发育及血清胃肠激素水平的影响,以期为临床治疗提供参考。方法本研究选取2020年8月—2021年10月河南省儿童医院郑州市儿童医院收治的89例晚期早产儿作为研究对象,采用随机数字表法将患儿分为观察组(n=45)与对照组(n=44)。对照组患儿给予早期微量喂养。观察组患儿在对照组基础上进行综合口腔运动干预。比较2组患儿恢复至出生体质量时间、2周时体质量增长幅度、2周时头围增长幅度。比较2组患儿干预前后血清胃动素(MOT)、胃泌素(GAS)水平。比较2组患儿干预前后新生儿神经行为评分标准(NBNA)评分。结果观察组患儿恢复至出生体质量时间短于对照组,2周时体质量增长幅度、2周时头围增长幅度均高于对照组,差异均有统计学意义(P<0.05)。干预前,2组患儿MOT、GAS水平比较,差异无统计学意义(P>0.05)。干预后,2组患儿MOT、GAS水平均高于干预前,且观察组高于对照组,差异均有统计学意义(P<0.05)。干预前,2组患儿NBNA中被动肌张力、主动肌张力、行为能力、一般情况、原始反射评分比较,差异无统计学意义(P>0.05)。干预后,2组患儿NBNA中被动肌张力、主动肌张力、行为能力、一般情况、原始反射评分均高于干预前,且观察组高于对照组,差异均有统计学意义(P<0.05)。结论早期微量喂养联合综合口腔运动干预应用于晚期早产儿护理中,能有效促使晚期早产儿生长发育,改善胃肠激素水平,效果显著,值得推广应用。Objective To investigate the effect of early microfeeding combined with integrated oral exercise intervention on growth and serum gastrointestinal hormones in late preterm infants,so as to provide a reference for clinical treatment.Methods Eighty-nine late preterm infants admitted to Henan Childen's Hospital/Zhengzhou Children's Hospital from August 2020 to October 2021 were selected as the study participants and assigned to an observation group(n=45)and a control group(n=44)by the random number table.Children in the control group received early microfeeding.Children in the observation group received integrated oral exercise intervention on the basis of the control group.The time to regain birth weight,weight gain at 2 weeks,and head circumference gain at 2 weeks were compared between the 2 groups.Serum motilin(MOT)and gastrin(GAS)levels were compared between the two groups before and after the intervention.The neonatal behavioral neurological assessment(NBNA)scores were compared between the 2 groups before and after the intervention.Results The time to regain birth weight in the observation group was shorter than that in the control group;the gains in body weight at 2 weeks and head circumference at 2 weeks were higher in the observation group than in the control group,with statistical significance(P<0.05).Before the intervention,there was no significant difference in MOT and GAS levels between the 2 groups(P>0.05).After the intervention,the levels of MOT and GAS in the two groups were higher than those before the intervention,and the observation group was higher than the control group,with statistical significance(P<0.05).Before the intervention,there was no significant difference in passive tone,active tone,behavior,general reaction,and primary reflexes scores in NBNA between the 2 groups(P>0.05).After the intervention,the passive tone,active tone,behavior,general reaction,and primary reflexes scores in NBNA of the two groups were higher than those before the intervention,and the observation group was higher t

关 键 词：晚期早产儿 早期微量喂养 口腔运动 生长发育 神经行为发育 血清胃肠激素 

分 类 号：R722.1[医药卫生—儿科]