甘草的主要化学成分及药理作用研究进展  

Research progress of main chemical constituents and pharmacological effects of Glycyrrhizae Radix et Rhizoma

作　　者：肖先 李春燕[1,2] 刘晓龙 薛金涛 XIAO Xian;LI Chunyan;LIU Xiaolong;XUE Jintao(School of Pharmacy,Xinxiang Medical University,Xinxiang 453003,Henan Province,China;Biological and Basic Medical Experimental Teaching Center,Sanquan College of Xinxiang Medical University,Xinxiang 453003,Henan Province,China)

机构地区：[1]新乡医学院药学院,河南新乡453003 [2]新乡医学院三全学院生物与基础医学实验教学中心,河南新乡453003

出　　处：《新乡医学院学报》2023年第3期280-285,共6页Journal of Xinxiang Medical University

基　　金：河南省重点研发与推广专项(河南省科技攻关计划)(编号:222102310566)。

摘　　要：甘草是我国的传统药材,其药用历史悠久,临床应用十分广泛,具有补脾益气、清热解毒、祛痰止咳、缓急止痛及调和诸药的作用。甘草的化学成分主要包括三萜皂苷类、黄酮类、甘草多糖类等。甘草的药理作用主要包括抗炎、抗肿瘤、抗菌、抗病毒、抗氧化和免疫调节等作用,且对心脑血管疾病、糖尿病和肝病等具有良好的治疗作用。本文归纳总结了甘草化学成分和药理作用的相关研究成果,旨在为甘草的深入研究、开发和临床利用提供参考。Glycyrrhizae Radix et Rhizoma is a traditional Chinese medicine with a long medicinal history and extensive clinical application.It has the functions of tonifying spleen and Qi,clearing heat and detoxification,eliminating phlegm and cough,relieving pain slowly and harmonizing various drugs.The chemical constituents of Glycyrrhizae Radix et Rhizoma mainly include triterpene saponins,flavonoids,glycyrrhiza polysaccharide,etc.The pharmacological effects of Glycyrrhizae Radix et Rhizoma mainly include anti-inflammatory,anti-tumor,anti-bacterial,anti-viral,anti-oxidation and immune regulation,etc.,and it has good therapeutic effects on cardiovascular and cerebrovascular diseases,diabetes and liver diseases.This paper summarized the related research results of chemical constituents and pharmacological effects of Glycyrrhizae Radix et Rhizoma,in order to provide a reference for further research and development and clinical use of Glycyrrhizae Radix et Rhizoma.

关 键 词：甘草 化学成分 药理作用 

分 类 号：R932[医药卫生—生药学]