曲前列尼尔治疗特发性肺动脉高压引起血小板减少1例  

Thrombocytopenia caused by treprostanil in the treatment of idiopathic pulmonary arterial hypertension:a case report

作　　者：张灿 常开丽 刘演龙 鲁一兵[1] 周旭 戴海龙[1] ZHANG Can;CHANG Kaili;LIU Yanlong;LU Yibing;ZHOU Xu;DAI Hailong(Clinical Medicine Center and Key Laboratory for Cardiovascular Disease of Yunnan Province,Department of Cardiology,Yan'an Affiliated Hospital of Kunming Medical University,Kunming,650051,China)

机构地区：[1]昆明医科大学附属延安医院心内科、云南省心血管疾病重点实验室、云南省心脏疾病临床医学中心,昆明650051

出　　处：《临床心血管病杂志》2023年第2期160-162,共3页Journal of Clinical Cardiology

基　　金：国家自然科学基金项目(No:82060018、81700438);云南省自然科学基金项目[No:202101AS070043、2019FE001(-269)]。

摘　　要：28岁女性患者,以活动后气促、心悸为主要临床表现,完善血常规、肝肾功能、传染病标志物、风湿免疫、心脏超声、胸部CT、肺动脉CT、右心导管、肺功能等检查,确诊特发性肺动脉高压。曲前列尼尔治疗肺动脉高压引起血小板减少的报道较少,在治疗中应注意监测患者血小板计数,以防止出血发生。A 28-year-old female patient,whose main clinical manifestations were dyspnea and palpitations after exercise,was diagnosed with idiopathic pulmonary arterial hypertension after blood routine,liver and kidney function,markers of infectious diseases,rheumatism immunity,cardiac ultrasound,chest CT,pulmonary artery CT,right cardiac catheterization,and pulmonary function.There are few reports of thrombocytopenia caused by treprostanil in the treatment of pulmonary arterial hypertension,we should pay attention to monitoring the change of platelet count to prevent bleeding.

关 键 词：肺动脉高压 前列环素 曲前列尼尔 血小板减少 

分 类 号：R544.1[医药卫生—心血管疾病]