缩宫素联合前列腺素类药物用于高危妊娠剖宫产产妇的效果  

Effect of oxytocin combined with prostaglandins on high-risk pregnancy cesarean section

作　　者：毛佳佳 Mao Jiajia(Department of Obstetrics and Gynecology,Sihong Hospital,Suqian 223900,China)

机构地区：[1]泗洪医院妇产科,江苏宿迁223900

出　　处：《实用妇科内分泌电子杂志》2022年第27期54-57,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨高危妊娠剖宫产产妇采用缩宫素联合卡前列素氨丁三醇治疗的效果。方法选取400例高危妊娠剖宫产产妇,根据随机数字表法分为对照组与研究组,每组200例。对照组采用缩宫素治疗,研究组采用缩宫素联合卡前列素氨丁三醇治疗。比较两组血红蛋白、凝血功能情况、临床指标、临床效果、不良反应发生情况。结果治疗前,两组血红蛋白(Hb)水平、凝血功能比较,差异无统计学意义(P>0.05);治疗后,研究组Hb值高于对照组,凝血酶原时间(PT)、凝血酶时间(TT)及纤维蛋白原(FIB)值均低于对照组,差异有统计学意义(P<0.05)。治疗后,研究组产后2、24 h出血量少于对照组,持续出血时间、住院时间均短于对照组,差异有统计学意义(P<0.05)。研究组总有效率高于对照组,差异有统计学意义(P<0.05)。两组比较不良反应发生率比较,差异无统计学意义(P>0.05)。结论缩宫素联合卡前列素氨丁三醇用于高危妊娠剖宫产产妇效果较好,可促进产妇凝血功能恢复,减少产后出血量,缩短住院时间,促进产妇恢复,不良反应发生率低,值得临床推广与应用。Objective To investigate the effect of high risk pregnancy cesarean section parturiens using oxytocin combined with carprost amine triol treatment.Methods A total of 400 cases of high-risk pregnancy cesarean section were selected and divided into control group and study group according to random number table method,200 cases in each group.The control group was treated with oxytocin,and the study group was treated with oxytocin combined with carprost amine triol.Hemoglobin,coagulation function,clinical indexes,clinical effects and the occurrence of adverse reactions were compared between the two groups.Results Before treatment,there was no significant difference in hemoglobin(Hb)level and coagulation function between the two groups(P>0.05).After treatment,the Hb value of the study group was higher than that of the control group,and the values of prothrombin time(PT),thrombin time(TT)and fibrinogen(FIB)were lower than those of the control group,with statistical significance(P<0.05).After treatment,the postpartum blood loss of 2 and 24 h in the study group was less than that in the control group,and the duration of bleeding and hospital stay were shorter than that in the control group,the difference was statistically significant(P<0.05).The total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The effect of oxytocin+caprost amine triol on high-risk pregnancy caesarean section is better,can promote the recovery of maternal coagulation function,reduce postpartum blood loss,shorten hospital stay,promote maternal recovery,low incidence of adverse reactions,worthy of clinical promotion and application.

关 键 词：缩宫素 卡前列素氨丁三醇 高危妊娠 剖宫产 产后出血 安全性 

分 类 号：R719.8[医药卫生—妇产科学]