Temporal characteristics of agarwood formation in Aquilaria sinensis after applying whole-tree agarwood-inducing technique  

作　　者：Yan Zhang Hui Meng Feifei Lyu Xiaohong Fan Peiwei Liu Xin He Ying Huang Bo Chen Yun Yang Jianhe Wei 

机构地区：[1]HainanProvincial Key Laboratory of Resources Conservation and Development of Southern Medicine,Hainan Branch Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences&Peking Union Medical College,Wanning 571533,China [2]National Engineering Laboratory for Breeding of Endangered Medicinal Materials,Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100193,China

出　　处：《Chinese Herbal Medicines》2023年第1期37-44,共8页中草药（英文版）

基　　金：supported by the funding from the National Key Research and Development Project of China (2018YFC1706400)。

摘　　要：Objective: Agarwood—a resinous wood produced by Aquilaria plants in response to injury or artificial induction—is a valuable medicinal and fragrance resource. Whole-Tree Agarwood-Inducing Technique(Agar-WIT) has been widely used to produce agarwood. However, the time-dependent characteristics of agarwood formation induced by Agar-WIT are yet to be clarified. To promote technologically efficient utilization and upgradation of Agar-WIT, the dynamic process and mechanism of agarwood formation were analyzed for one year.Methods: Agarwood formation percentage, barrier layer microscopic properties, extract levels, compound level, and characteristic chromatograms of agarwood were examined by referring to the Chinese Pharmacopeia(2020 version).Results: Agar-WIT could maintain a high percentage of agarwood formation over one year compared with that of healthy plants. Alcohol-soluble extract and agarotetrol levels showed fluctuating cyclic changes with peaks occurring first during the fifth and sixth months, and subsequently in the 11th month.Aquilaria trees subjected to Agar-WIT treatment for 1–12 months showed significant characteristics of a dynamic agarwood formation process. The barrier layer began to appear in the fourth month after treatment. Alcohol-soluble extractive levels in agarwood formed in the second month, and thereafter,exceeded 10.0%, and agarotetrol in agarwood produced after four months or later, exceeded 0.10%.Conclusion: According to the Chinese Pharmacopoeia, alcohol-soluble extractive levels in agarwood should not be less than 10.0% and agarotetrol level should exceed 0.10%. After four months of Agar-WIT treatment, the formed agarwood theoretically met these standards and was suitable for developed and utilization. However, the optimal harvest time was found to be the 11th month, followed by the sixth month after Agar-WIT treatment. Therefore, Agar-WIT resulted in swift agarwood formation and stable accumulation of alcohol-soluble extracts and agarotetrol. Thus, this method is efficient for la

关 键 词：agarotetrol AGARWOOD alcohol-soluble extractive Aquilaria sinensis(Lour.)Gilg whole-tree agarwood-inducing technique(Agar-WIT) 

分 类 号：R284.1[医药卫生—中药学]