羊水胎粪污染与宫内感染的相关性  

Correlation between meconium-stained amniotic fluid and intrauterine infection

作　　者：刘敬 Liu Jing(Department of Neonatology,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100021,China)

机构地区：[1]首都医科大学附属北京朝阳医院新生儿科,北京100021

出　　处：《中华实用儿科临床杂志》2023年第3期203-206,共4页Chinese Journal of Applied Clinical Pediatrics

摘　　要：长期以来,羊水胎粪污染的主要原因被认为是胎儿缺氧。但近期有研究发现在胎粪及羊水中培养出多种病原微生物,而在被胎粪污染的羊水中所含有的菌种则更丰富;临床观察也发现羊水胎粪污染与胎儿-新生儿感染和孕产妇围生期感染密切相关,这些胎儿在出生不久即出现感染症状或感染相关实验室指标的异常。因此,认为宫内感染可能是羊水胎粪污染的重要原因之一。加深对羊水胎粪污染原因的认识,有助于改变对患儿的临床管理和改善其预后。Fetal hypoxia has long been described as the main cause of meconium-stained amniotic fluid(MSAF).However,recent studies have reported the presence of a variety of pathogenic microorganisms in meconium and amniotic fluid,and even more bacterial species in MSAF.Clinical observations also revealed that MSAF was closely related to fetal-neonatal infection and perinatal infection of pregnant women.Shortly after birth,the fetuses with MSAF developed infectious symptoms or showed abnormalities in infection-related laboratory indicators.Therefore,intrauterine infection may be one major cause of MSAF.To further our understanding of the factors leading to MSAF will improve the clinical management and prognosis of infants.

关 键 词：羊水胎粪污染 宫内感染 胎儿窘迫 胎粪吸入 婴儿 新生 

分 类 号：R714.5[医药卫生—妇产科学]