持续性非卧床腹膜透析患者体脂率的影响因素分析  

Impact factors analysis of body fat rate in continuous ambulatory peritoneal dialysis patients

作　　者：杨雪 房莉莉 张雨薇 郑红光 Yang Xue;Fang Lili;Zhang Yuwei;Zheng Hongguang(Department of Nephrology,General Hospital of Northern Theater Command,Shenyang 110016,China)

机构地区：[1]北部战区总医院肾内科,沈阳110016

出　　处：《中国临床实用医学》2022年第6期48-52,共5页China Clinical Practical Medicine

摘　　要：目的探讨持续性非卧床腹膜透析(CAPD)患者体脂率的影响因素。方法本研究为回顾性病例对照研究,选取2016年1月至2020年12月北部战区总医院肾内科收治的83例CAPD患者,男44例,女39例,年龄(57.92±12.15)岁,年龄范围为26~80岁。根据WHO成年男女肥胖标准将其分为肥胖组(n=31)与非肥胖组(n=52)。比较两组患者的一般指标、透析相关指标、临床特征指标。结果肥胖组患者的年龄、女性所占比例、体质量指数、腰围、锥度指数、体脂率、脂肪量、脂肪指数、总蛋白、甘油三酯、胆固醇、C反应蛋白(CRP)、红细胞沉降率[(62.30±11.13)岁、61.3%、(26.05±3.39)kg/m^(2)、(87.17±8.26)cm、1.21±0.10、(33.35±6.82)%、(23.72±4.51)kg、(8.71±2.23)kg/m^(2)、(69.93±9.55)g/L、(2.64±1.68)mmol/L、(4.60±0.96)mmol/L、(10.87±8.17)mmol/L、(48.23±29.04)mm/h]高于非肥胖组[(55.43±12.09)岁、38.5%、(23.74±4.15)kg/m^(2)、(75.41±8.19)cm、1.10±0.78、(21.25±8.13)%、(13.98±5.79)kg、(5.16±2.30)kg/m^(2)、(65.37±8.75)g/L、(1.89±0.86)mmol/L、(4.20±0.77)mmol/L、(6.36±5.41)mmol/L、(34.56±26.04)mm/h],瘦体质量、瘦体指数、细胞内液量、血肌酐、高密度脂蛋白、血磷、钙磷乘积[(44.86±9.87)kg、16.49±2.81、(20.94±4.63)L、(710.90±161.72)μmol/L、(1.05±0.26)mmol/L、(1.46±0.26)mmol/L、(3.18±0.63)mmol2/L^(2)]均低于非肥胖组[(50.30±11.75)kg、(17.82±2.98)kg/m^(2)、(23.61±5.52)L、(836.53±247.56)μmol/L、(1.29±0.21)mmol/L、(1.63±0.36)mmol/L、(3.53±0.76)mmol2/L^(2)],差异有统计学意义(P<0.05)。CRP与体脂率、腰围、脂肪量、脂肪指数、锥度指数均成正相关。体脂率与甘油三酯、胆固醇均成正相关。结论体脂率水平有可能成为预测CAPD患者心血管疾病风险的重要指标。Objective To explore the influencing factors of body fat rate in patients with continuous ambulatory peritoneal dialysis.Methods This study was a retrospective case-control study.A total of 83 patients with continuous ambulatory peritoneal dialysis(CAPD),including 44 males and 39 females,aged(57.92±12.15)years old,ranging from 26 to 80 years old,were selected from the department of nephrology,General Hospital of Northern Theater Command from January 2016 to December 2020.According to WHO adult male and female obesity standards,83 CAPD patients were divided into obese group(n=31)and non-obese group(n=52).The general indexes,dialysis related indexes and clinical characteristic indexes of the two groups were compared.Results The age,the proportion of females,body mass index,waist circumference,cone index,body fat rate,fat mass,fat index,total protein,triglyceride,cholesterol,C-reactive protein(CRP)and erythrocyte sedimentation rate in the obese group[(62.30±11.13)years old,61.3%,(26.05±3.39)kg/m^(2),(87.17±8.26)cm,1.21±0.10,(33.35±6.82)%,(23.72±4.51)kg,(8.71±2.23)kg/m^(2),(69.93±9.55)g/L,(2.64±1.68)mmol/L,(4.60±0.96)mmol/L,(10.87±8.17)mmol/L,(48.23±29.04)mm/h]were higher than those in the non-obese group[(55.43±12.09)years old,38.5%,(23.74±4.15)kg/m^(2),(75.41±8.19)cm,1.10±0.78,(21.25±8.13)%,(13.98±5.79)kg,(5.16±2.30)kg/m^(2),(65.37±8.75)g/L,(1.89±0.86)mmol/L,(4.20±0.77)mmol/L,(6.36±5.41)mmol/L,(34.56±26.04)mm/h],lean body mass,lean body index,intracellular fluid volume,blood creatinine,high density lipoprotein,blood phosphorus level and calcium phosphorus product[(44.86±9.87)kg,16.49±2.81,(20.94±4.63)L,(710.90±161.72)μmol/L,(1.05±0.26)mmol/L,(1.46±0.26)mmol/L,(3.18±0.63)mmol2/L^(2)]were all lower than those in the non-obese group[(50.30±11.75)kg,(17.82±2.98)kg/m^(2),(23.61±5.52)L,(836.53±247.56)μmol/L,(1.29±0.21)mmol/L,(1.63±0.36)mmol/L,(3.53±0.76)mmol2/L^(2)],the differences were statistically significant(P<0.05).CRP was positively correlated with body fat rate,waist circum

关 键 词：持续性非卧床腹膜透析 体脂率 肥胖 终末期肾病 体质量指数 

分 类 号：R459.5[医药卫生—治疗学]