口腔过敏综合征的研究进展  

Research progress of oral allergy syndrome

作　　者：樊壮壮 陆支越[1] 金建秋[1] Fan Zhuangzhuang;Lu Zhiyue;Jin Jianqiu(Department of Stomatology,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]北京医院口腔科、国家老年医学中心、中国医学科学院老年医学研究院,北京100730

出　　处：《中华预防医学杂志》2023年第3期341-347,共7页Chinese Journal of Preventive Medicine

基　　金：中央高水平医院临床科研业务费(BJ-2022-177);国家重点研发计划(2020YFC2009005)。

摘　　要：口腔过敏综合征(oral allergy syndrome,OAS)是IgE介导的Ⅰ型超敏反应,花粉过敏患者进食含有同源致病变应原的新鲜水果或蔬菜后,出现口咽部过敏症状,偶尔伴发全身症状,属于呼吸道变应原与食物变应原因结构相似产生交叉免疫反应的食物过敏特殊类型。目前,国内相关研究和关注较少。系统掌握口腔过敏综合征的定义、流行病学特征、病理学机制、诊断、预防和治疗,对其防控有重要意义,本文对口腔过敏综合征的研究进展进行阐述,为临床提高对此病的诊断和鉴别诊断水平提供参考和预防依据。Oral allergy syndrome(OAS)is an IgE-mediated hypersensitivity.Patients with pollen allergy will experience oropharyngeal allergy after eating fresh fruits or vegetables containing homologous pathogenesis-related allergen,occasionally accompanied by systemic symptoms,it is a special type of food hypersensitivity in which respiratory allergens and food allergens are similar structurally and lead to the cross-reactivity.At present,there is little research and attention to it in China.To master the definition,epidemiological characteristics,pathological mechanism,diagnosis,prevention and treatment of OAS is very important to the prevention and control of OAS.This article reviews the research progress of OAS,providing reference and prevention basis for clinicians to improve the diagnosis and differential diagnosis of OAS.

关 键 词：口腔过敏综合征 花粉食物过敏综合征 食物过敏 致病变应原 交叉过敏反应 免疫疗法 

分 类 号：R593.1[医药卫生—内科学]