基于2019年全球疾病负担研究数据分析1990—2019年中国高血压心脏病疾病负担变化趋势  

The 1990—2019 trends in the burden of hypertensive heart disease in China based on data from the Global Burden of Disease Study 2019

作　　者：张记收 王梦龙[1] 刘剑芳[1] 徐瑶[1] 赵蒙蒙 徐姝婉 潘威 殷征 魏成 万军[1] ZHANG Jishou;WANG Menglong;LIU Jianfang;XU Yao;ZHAO Mengmeng;XU Shuwan;PAN Wei;YIN Zheng;WEI Cheng;WAN Jun(Department of Cardiology,Renmin Hospital of Wuhan University,Cardiovascular Research Institute,Wuhan University,Hubei Key Laboratary of Cardiology,Wuhan,Hubei 430060,China)

机构地区：[1]武汉大学人民医院心内科,武汉大学心血管病研究所,心血管病湖北省重点实验室,湖北武汉430060

出　　处：《中华高血压杂志》2023年第2期141-149,共9页Chinese Journal of Hypertension

基　　金：国家自然科学基金(82070436)。

摘　　要：目的分析1990—2019年我国高血压心脏病总人群,以及不同性别、不同年龄群体的疾病负担变化趋势。方法利用2019年全球疾病负担研究(GBD)数据,分析1990—2019年高血压心脏病年患病人数、死亡人数、伤残调整寿命年(DALYs)和患病率、死亡率、DALYs率。结果1990—2019年,我国高血压心脏病年龄标化患病率呈先降低后升高趋势。与1990年相比,2019年我国高血压心脏病标化患病率下降6.0%(1990年标化患病率为461.0/10万,2019年为433.5/10万),其中男性标化患病率下降幅度大于女性,而男、女性15~<50岁群体患病率却明显上升。1990—2019年我国高血压心脏病年龄标化死亡率和DALYs率均呈先降低后升高再降低趋势。与1990年相比,2019年我国高血压心脏病标化死亡率和DALYs率分别下降51.2%和54.8%,其中女性下降幅度大于男性,并且以上现象在15~<50岁、50~<70岁、≥70岁各年龄段表现一致。在高血压心脏病死亡归因危险因素方面,2019年与男性患者死亡相关的前4位危险因素分别是高收缩压、高盐膳食、高体质量指数(BMI)和饮酒,而女性前4位分别是高收缩压、高BMI、高盐膳食和低气温。结论1990—2019年我国高血压心脏病患病率整体呈先降低后升高趋势,高血压心脏病死亡和伤残负担呈先降低后升高再降低趋势,并呈现性别和年龄差异特点。Objective To analyze the burden of hypertensive heart disease(HHD)from 1990 to 2019 in the total population and in different sex and age subgroups in China.Methods Number of HHD cases,deaths and disability-adjusted life years(DALYs),prevalence rate,mortality and DALYs rate from 1990 to 2019 were analyzed based on the data of Global Burden of Disease Study(GBD)2019.Results From 1990 to 2019,the age-standardized prevalence of HHD in China first decreased and then increased.Compared with the data in 1990,the standardized prevalence of HHD decreased by 6.0%in 2019(461.0/100000 in 1990 vs 433.5/100000 in 2019).The prevalence in males decreased more than that in females,while the prevalence in both males and females aged 15-<50 significantly increased.From 1990 to 2019,the age-standardized mortality and DALYs rate of HHD in China showed a trend of first decreasing,subsequent increasing and then decreasing.Compared with the data in 1990,the standardized mortality and DALYs rate decreased by 51.2%and 54.8%in 2019,respectively,with a greater decrease in females than in males,and these trends were consistent in all age groups(including 15-<50,50-<70 and≥70 years).In terms of attributable risk factors for death from HHD,the top 4 risk factors in males in 2019 were high systolic blood pressure,high salt diet,high body mass index(BMI)and alcohol consumption,while the top 4 risk factors in females were high systolic blood pressure,high BMI,high salt diet and low air temperature.Conclusion From 1990 to 2019,the prevalence of HHD in China showed a trend of first decreasing and then increasing,and the burden(death and disability)of HHD showed a trend of first decreasing,subsequent increasing and then decreasing,with sex and age differences.

关 键 词：全球疾病负担研究 高血压心脏病 性别 年龄 疾病负担 

分 类 号：R541.3[医药卫生—心血管疾病]