Global prevalence of Ascaris infection in humans(2010–2021):a systematic review and meta-analysis  

作　　者：Celia Holland Mahdi Sepidarkish Gwendoline Deslyper Ali Abdollahi Soghra Valizadeh Abolfazl Mollalo Sanaz Mahjour Sahar Ghodsian Ali Ardekani Hamed Behniafar Robin B.Gasser Ali Rostami 

机构地区：[1]不详 [2]Department of Veterinary Biosciences,Melbourne Veterinary School,Faculty of Veterinary and Agricultural Sciences,The University of Melbourne,Parkville,VIC,Australia [3]Infectious Diseases and Tropical Medicine Research Center,Health Research Institute,Babol University of Medical Sciences,Babol,Iran

出　　处：《Infectious Diseases of Poverty》2022年第6期94-95,共2页贫困所致传染病（英文）

摘　　要：Background:Ascariasis is one of the most important neglected tropical diseases of humans worldwide.The epidemiology of Ascaris infection appears to have changed with improvements in sanitation and mass drug administration,but there is no recent information on prevalence worldwide.Here,we performed a systematic review and meta-analysis to assess the global prevalence of human Ascaris infection from 2010 to 2021.Methods:We searched MEDLINE/PubMed,and Scopus databases for studies measuring prevalence of Ascaris infection,published between 1 January 2010 and 1 January 2022.We included studies of the general human population in endemic regions,which used accepted coprodiagnostic methods,and excluded studies of people with occupations with an increased risk or probability of ascariasis and/or specifc diseases other than ascariasis.We applied randomefects models to obtain pooled prevalence estimates for six sustainable development goal regions of the world.We extrapolated the prevalence estimates to the global population in 2020,to estimate the number of individuals with Ascaris infection.We conducted multiple subgroup and meta-regression analyses to explore possible sources of heterogeneity,and to assess relationships between prevalence estimates and demographic,socio-economic,geoclimatic factors.Results:Of 11,245 studies screened,we analysed 758 prevalence estimates for a total number of 4,923,876 participants in 616 studies from 81 countries.The global prevalence estimated was 11.01%(95%confdence interval:10.27–11.78%),with regional prevalences ranging from 28.77%(7.07–57.66%)in Melanesia(Oceania)to 1.39%(1.07–1.74%)in Eastern Asia.We estimated that~732(682–782)million people harboured Ascaris worldwide in 2021.The infected people in Latin America and the Caribbean region had a higher prevalence of high intensity infection(8.4%,3.9–14.1%).Prevalence estimates were higher in children,and people in rural communities or in countries or regions with lower income and human development indices.There was a trend f

关 键 词：ASCARIS Global prevalence Intensity of infection Systematic review META-ANALYSIS 

分 类 号：R52[医药卫生—内科学] R181.3[医药卫生—临床医学]