Re-emerging threat of Trypanosoma cruzi vector transmission in El Salvador, update from 2018 to 2020  

作　　者：Marvin Stanley Rodriguez Yuko Nitahara Michelle Cornejo Kevin Siliezar Rafael Grande Ana Gonzalez Kotaro Tasaki Yu Nakagama Yu Michimuko Yoko Onizuka Junko Nakajima-Shimada Jose Eduardo Romero Jose Ricardo Palacios Carmen Elena Arias Wilam Mejia Yasutoshi Kido Ricardo Cardona Alvarenga 

机构地区：[1]Department of Virology and Parasitology,Graduate School of Medicine,Osaka Metropolitan University,1-4-3 Asahi-machi,Abeno-ku,Osaka 545-8585 Japan [2]不详

出　　处：《Infectious Diseases of Poverty》2022年第4期101-102,共2页贫困所致传染病（英文）

摘　　要：Background:Since the late twentieth century,Chagas disease gained global attention to suppress the vector burden as a main control strategy in endemic countries.In Central America,multi-national initiative successfully achieved significant reduction in the estimated disease prevalence as well as elimination of the region's principal vector species at the time in 2012.While the last decade has witnessed significant changes in ecosystem-such as urbanization and replacement of the main vector species-that can possibly affect the vector's habitation and residual transmission,the up-to-date vector burden in the region has not been evaluated thoroughly due to the cessation of active vector surveillance.The aim of this study was to update the risk of vector-borne Trypanosoma cruzi infection in El Salvador,the top Chagas disease-endemic country in Central America.Methods:A nationwide vector survey was conducted in the domestic environment of El Salvador from September 2018 to November 2020.The selection of the houses for inspection was based on expert purposeful sampling.Infection for T.cruzi was examined by microscopic observation of the insects'feces,followed by a species confrmation using PCR.The data were analyzed using R software version 4.1.3.Proportion estimates with 95%confidence intervals were inferred using the Jeffrey's method provided under the epiR package.Results:A total of 1529 Triatoma dimidiata was captured from 107 houses(infestation rate,34.4%;107/311)in all the fourteen departments of the country visited within the period;prevalence of T.cruzi infection was as high as 10%(153/1529).In the country,domestic T.dimidiata infestation was distributed ubiquitously,while T.cruzi infection rates varied across the departments.Five out of fourteen departments showed higher infection rates than the average,suggesting sporadic high-risk areas in the country.Conclusions:Our comprehensive study revealed substantial T.cruzi infection of T.dimidiata across the country,indicating potential active transmission of the di

关 键 词：Chagas disease Vector transmission TRIATOMINE Trypanosoma cruzi Triatoma dimidiata 

分 类 号：R531[医药卫生—内科学]