布地奈德混悬液联合特布他林雾化液治疗慢性阻塞性肺疾病的效果及对患者炎性指标的影响  

Effect of Budesonide Suspension Combined with Terbutaline Atomization in the Treatment of Chronic Obstructive Pulmonary Disease and the Impact on Inflammatory Indicators

作　　者：李晓琳[1] 吴景硕[1] 刘正[1] 朱惠源[1] 张钟[1] 马星 LI Xiaolin;WU Jingshuo;LIU Zheng;ZHU Huiyuan;ZHANG Zhong;MA Xing(Respiratory Intensive Care Unit,Zhengzhou Second People's Hospital,Zhengzhou 450000,China)

机构地区：[1]郑州市第二人民医院呼吸与危重症医学科,河南郑州450000

出　　处：《临床医学工程》2023年第3期341-342,共2页Clinical Medicine & Engineering

摘　　要：目的探讨布地奈德混悬液联合特布他林雾化液治疗慢性阻塞性肺疾病(COPD)的效果及对患者炎性指标的影响。方法选择2019年1月至2021年6月我院收治的80例COPD患者,随机分为观察组与对照组各40例。对照组采用布地奈德混悬液单独治疗,观察组予以布地奈德混悬液联合特布他林雾化液治疗。比较两组的治疗效果、血气指标与炎性指标。结果观察组治疗总有效率为95.00%,高于对照组的77.50%(P<0.05)。治疗后,观察组PaCO_(2)低于对照组,PaO_(2)、SaO_(2)高于对照组(P<0.05)。治疗后,观察组CRP、WBC与中性粒细胞水平均低于对照组(P<0.05)。结论布地奈德混悬液联合特布他林雾化液治疗COPD的效果显著,可有效改善患者血气指标与炎性指标水平,促进患者病情康复。Objective To explore the effect of budesonide suspension combined with terbutaline atomization in the treatment of chronic obstructive pulmonary disease(COPD)and the impact on inflammatory indicators.Methods 80 COPD patients admitted to our hospital from January 2019 to June 2021 were randomly divided into observation group and control group,with 40 cases in each group.The control group was only treated with budesonide suspension,and the observation group was treated with budesonide suspension combined with terbutaline atomization.The treatment effect,blood gas indicators and inflammatory indicators of the two groups were compared.Results The total effective rate of treatment in the observation group was 95.00%,higher than 77.50% in the control group(P<0.05).After treatment,the PaCO_(2) of the observation group was lower than that of the control group,and the PaO_(2) and SaO_(2) were higher than those of the control group(P<0.05).After treatment,the CRP,WBC and neutrophil levels of the observation group were lower than those of the control group(P<0.05).Conclusions Budesonide suspension combined with terbutaline atomization in the treatment of COPD has significant effect,which can effectively improve the levels of blood gas indicators and inflammatory indicators and promote the recovery of patients.

关 键 词：布地奈德混悬液 特布他林雾化液 慢性阻塞性肺疾病 血气指标 炎性指标 

分 类 号：R563.9[医药卫生—呼吸系统]