对甲氧基苯甲醛合成工艺研究进展  

Research Progress in Synthesis ofp-Methoxybenzaldehyde

作　　者：王忠冬 韩帅 李为民[2] Wang Zhongdong;Han Shuai;Li Weimin(Jiangsu Feiya Chemical Industry Co.,Ltd.,Nantong 226634,China;College of Petroleum and Chemical Engineering,Changzhou University,Changzhou 213164,China)

机构地区：[1]江苏飞亚化学工业股份有限公司,江苏南通226634 [2]常州大学石油与化工学院,江苏常州213164

出　　处：《山东化工》2023年第2期76-78,81,共4页Shandong Chemical Industry

基　　金：2021年江苏省研究生实践创新计划项目(SJCX21_1255)。

摘　　要：综述了对甲氧基苯甲醛合成工艺的研究进展和成果,重点阐述了以茴脑、对甲苯酚为原料的合成方法。以茴脑为原料将其烯烃双键氧化成醛基,按照氧化方法分为3种;以对甲苯酚为原料需要两步,对甲苯酚的酚羟发生氧甲基化反应得到对甲氧基甲苯,甲基氧化成醛基得到对甲氧基苯甲醛。这两种原料的催化体系条件温和,操作工艺简单,环境友好,具有良好的工业应用前景。The research progress and achievements in the synthesis of p-methoxybenzaldehyde were reviewed,with emphasis on the synthesis methods using anethole and p-cresol as raw materials.The olefin double bond of anethole is oxidized to aldehyde group,which can be divided into three kinds according to the oxidation method;Taking p-cresol as raw material requires two steps.The phenol hydroxyl of p-cresol undergoes oxygen methylation reaction to obtain p-Methoxytoluene,and methyl is oxidized to aldehyde group to obtain p-methoxybenzaldehyde.The catalytic system conditions of these two raw materials are mild,the operation process is simple,environment-friendly,and have good industrial application prospects.

关 键 词：茴脑 氧化双键 对甲苯酚 氧甲基化 甲基氧化 

分 类 号：TQ655[化学工程—精细化工]