95例癫痫患者睡眠结构及呼吸相关事件研究  

Sleep structure and respiratory events in patients with epilepsy:An analysis of 95 cases

作　　者：吴美娜[1] 林芳[1] 季晓林[1] 严金柱[1] WU Meina;LIN Fang;JI Xiaolin(Department of Neurology,Sleep Medical Center,Fujian Province Governmental Hospital(The Affiliated Hospital of Fujian Health College),Fuzhou 350003,China)

机构地区：[1]福建省级机关医院(福建卫生职业技术学院附属医院)神经内科睡眠医学中心,福建福州350003

出　　处：《中风与神经疾病杂志》2023年第3期212-215,共4页Journal of Apoplexy and Nervous Diseases

基　　金：福建省自然科学基金资助项目(No.2019J01095)。

摘　　要：目的探讨癫痫患者睡眠结构及呼吸相关事件的相关性。方法收集2018年3月-2022年3月就诊我院的癫痫患者95例及对照组66例,通过多导睡眠监测,比较癫痫组和对照组的睡眠结构及呼吸相关事件差异。结果与对照组比较,癫痫组的REM期睡眠持续时间、R%减少,差异有统计学意义;低通气最长时间延长,最低氧饱降低,差异有统计学意义。结论癫痫患者存在睡眠结构改变,癫痫患者合并阻塞性睡眠呼吸暂停低通气综合征,更易出现低氧血症。Objective To investigate the association between sleep structure and respiratory events in patients with epilepsy.Methods A total of 95 patients with epilepsy and 66 control patients who attended our hospital from March 2018 to March 2022 were enrolled,and polysomnography was used to compare sleep structure and respiratory events between the epilepsy group and the control group.Results Compared with the control group,the epilepsy group had significant reductions in REM sleep duration and R%,a significant increase in the longest duration of hypoventilation,and a significant reduction in the lowest oxygen saturation.Conclusion Changes in sleep structure are observed in patients with epilepsy,and patients with epilepsy and obstructive sleep apnea-hypopnea syndrome tend to develop hypoxemia.

关 键 词：癫痫 快速眼球运动睡眠 阻塞性睡眠呼吸暂停 低氧血症 

分 类 号：R338.63[医药卫生—人体生理学] R742.1[医药卫生—基础医学]