喉罩全麻中麻醉诱导期静脉靶控输注右美托咪定复合丙泊酚价值体会  

Value Experience of Intravenous Target-Controlled Infusion ofDexmedetomidine Combined with Propofol in InductionPeriod During Laryngeal Mask Anesthesia

作　　者：王丁木 王玉 袁竹清 WANG Dingmu;WANG Yu;YUAN Zhuqing(Xinghua City People's Hospital of Jiangsu,Huaining,Anhui 225700)

机构地区：[1]江苏省兴化市人民医院,安徽怀宁225700

出　　处：《智慧健康》2023年第2期108-110,115,共4页Smart Healthcare

摘　　要：目的 探究喉罩全麻中麻醉诱导期静脉靶控输注右美托咪定复合丙泊酚应用效果及价值。方法 将160例在本院行喉罩全麻手术的患者随机分为参照组和观察组,每组各80例,参照组患者麻醉诱导期静脉靶控输注丙泊酚,观察组患者联合右美托咪定进行麻醉,比较两组患者麻醉效果。结果 观察组患者Ce50、Ce95和丙泊酚用量均高于参照组(P<0.05);观察组患者T1、T2和T3时的HR、MAP和SpO_(2)水平明显高于参照组(P<0.05);观察组患肢自主呼吸恢复时间、喉罩拔除时间及恢复室Steward分数≥4分时间均早于参照组(P<0.05);观察组患者术后躁动及恶心呕吐发生率均低于参照组患者(P<0.05)。结论 喉罩全麻中麻醉诱导期静脉靶控输注右美托咪定复合丙泊酚,能够减少手术患者丙泊酚使用剂量,维持术中血流动力学的稳定,降低术后不良反应发生率,更有利于患者的术后恢复。Objective To explore effect and value of intravenous target-controlled infusion of dexmedetomidine combined with propofol during induction of general anesthesia with laryngeal mask.Methods The paper chose 160 patients with laryngeal mask surgery in our hospital,and divided them into reference group and observation group randomly,with 80 cases in each group.Reference group was treated with intravenous target-controlled infusion of propofol during anesthesia induction,and observation group were anesthetized with dexmedetomidine.Anesthetic effect between two groups was compared.Results Dosage of Ce50,Ce95 and propofol in observation group was higher than control group(P<0.05);levels of HR,MAP and SpO_(2) at T1,T2 and T3 in observation group were significantly higher than control group(P<0.05);recovery time of spontaneous respiration of affected limbs,time of laryngeal mask removal and time of Steward scores≥4 in recovery room in observation group was earlier than control group(P<0.05).Incidence of postoperative restlessness and nausea and vomiting in observation group was lower than control group(P<0.05).Conclusion Intravenous target-controlled infusion of dexmedetomidine combined with propofol during anesthesia induction in LMA general anesthesia can reduce dosage of propofol for patients with surgery,maintain stability of hemodynamics during surgery,reduce incidence of postoperative adverse reactions,which is conducive to postoperative recovery of patients.

关 键 词：喉罩全麻 麻醉诱导期 静脉靶控输注 右美托咪定 丙泊酚 

分 类 号：R614.2[医药卫生—麻醉学]