下肢皮肤罗道病1例报道并探讨其可能发生机制  

Report of a Case of Cutaneous Rhodopsin of the Lower Extremities and Discussion of its Possible Mechanism of Oc⁃currence

作　　者：孔韦奇 陈中皓[1] 廖作富 KONG Wei-qi;CHEN Zhong-hao;LIAO Zuo-fu(Department of General Surgery,Tongren Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,200336,China)

机构地区：[1]上海交通大学医学院附属同仁医院普外科,上海200336

出　　处：《黑龙江医学》2023年第6期685-688,共4页Heilongjiang Medical Journal

摘　　要：目的:探讨罗道病又称窦组织细胞增生伴巨大淋巴结病(Rosai Dorfman,RDD)的发病机制、临床表现、诊断治疗及预后。方法:回顾性分析上海交通大学医学院附属同仁医院收治的1例RDD患者的临床资料,并结合文献进行复习。结果:该患者术后病理诊断结合免疫酶标记结果符合RDD,术后病理免疫组化指标:S-100(+),CD68(部分阳性),CD1a(-)。结论:RDD较为罕见,需要影像科、外科、病理科和肿瘤科医生组成的团队进行早期诊断治疗。Objective:To investigate the pathogenesis,clinical manifestations,diagnosis,treatment and prognosis of Rosai Dorf⁃man giant lymphadenopathy(RDD)with histiocytosis of sinus.Methods:The clinical data of one patient with RDD were retrospec⁃tively analyzed,and the literature was reviewed.Results:The postoperative pathological diagnosis of the patient combined with the results of immunoenzyme labeling were consistent with RDD.The postoperative pathological immunohistochemical indexes were S-100(+),CD68(partially positive),and CD1a(-).Conclusion:RDD is rare and requires early diagnosis and treatment by a team of imaging,surgery,pathology,and oncology physicians.

关 键 词：罗道病 窦组织增生性淋巴结 免疫缺陷 

分 类 号：R551.2[医药卫生—血液循环系统疾病]