中药“喷灌疗法”治疗普通型手足口病的临床效果、安全性及经济性  

Clinical effect, safety and economy of traditional Chinese medicine "sprinkling irrigation therapy" in the treatment of common hand-foot-mouth disease

作　　者：刘飞 程兰[2] 熊艳 朱春晖[1] LIU Fei;CHENG Lan;XIONG Yan;ZHU Chunhui(Department of Infectious Diseases,Jiangxi Provincial Children's Hospital,Jiangxi Province,Nanchang330000,China;Department of Hematology,Jiangxi Provincial Children's Hospital,Jiangxi Province,Nanchang330000,China)

机构地区：[1]江西省儿童医院感染科,江西南昌330000 [2]江西省儿童医院血液科,江西南昌330000

出　　处：《中国当代医药》2023年第9期82-86,共5页China Modern Medicine

基　　金：江西省重点研发计划项目(20161ACG70017);江西省中医药科研课题项目(2019A296)。

摘　　要：目的 探讨中药“喷灌疗法”治疗普通型手足口病的临床效果、安全性及经济性。方法 选取2021年1月至6月在江西省儿童医院感染科住院的90例1~5岁普通型手足口病患儿为研究对象,采用随机数字表法分为对照组、开喉剑组和联合组,每组各30例。比较三组患儿的一般资料、临床症状和体征消退时间、不良反应发生率、重症转化情况、治疗前后炎症因子水平及住院时间、住院费用的情况。结果 联合组临床症状和体征消退时间均短于开喉剑组和对照组,差异有统计学意义(P<0.05);三组患儿不良反应发生率比较,差异无统计学意义(P>0.05);联合组治疗后的炎症因子水平均低于开喉剑组和对照组,差异有统计学意义(P<0.05);联合组的住院时间短于开喉剑组和对照组,住院费用少于开喉剑组和对照组,差异有统计学意义(P<0.05)。结论 中药“喷灌疗法”治疗普通型手足口病给药方式简便、临床疗效显著,有利于缩短患儿发热、皮疹/疱疹、口腔溃疡等症状消退时间和住院时间,大大降低医疗费用,同时能有效调节机体炎症因子,安全性好。Objective To explore the clinical effect,safety and economy of traditional Chinese medicine"sprinkling irrigation therapy"in the treatment of common hand-foot-mouth disease.Methods A total of 90 children with common hand,foot and mouth disease aged 1-5 years who were hospitalized in the Department of Infectious Diseases of Jiangxi Provincial Children's Hospital from January to June 2021 were selected as the research objects.They were divided into control group,Kaihoujian group and combination group by random number table method,with 30 cases in each group.The general data,the regression time of clinical symptoms and signs,the incidence of adverse reactions,the transformation of severe cases,the levels of inflammatory factors before and after treatment,the length of hospital stay and the cost of hospitalization were compared among the three groups.Results The regression time of clinical symptoms and signs in the combined group were shorter than those in the Kaihuijian group and the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).After treatment,the levels of inflammatory factors in the combination group were lower than those in the Kaihuijian group and the control group,and the differences were statistically significant(P<0.05).The hospitalization time of the combination group were shorter than those of the Kaihoujian group and the control group,and the hospitalization cost was less than those of the Kaihoujian group and the control group,and the differences were statistically significant(P<0.05).Conclusion Traditional Chinese medicine"sprinkling irrigation therapy"in the treatment of common hand-foot-mouth disease is simple and effective,which is conducive to shorten the disappearance time of fever,rash/herpes,oral ulcer and other symptoms and hospitalization time,greatly reduce medical costs,and can effectively regulate the body's inflammatory factors,with good safety.

关 键 词：儿童 手足口病 喷灌疗法 开喉剑喷雾剂 发热 

分 类 号：R725.1[医药卫生—儿科]