单胎足月妊娠晚期宫颈不成熟因素分析  

Factor analysis of cervical immaturity in the late term pregnancy of single fetus

作　　者：马兰[1] 亢雪峰[1] 毛思思 MA Lan;KANG Xuefeng;MAO Sisi(Department of Obstetrics and Gynecology,Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine,Guangdong Province,Zhongshan528400,China)

机构地区：[1]广州中医药大学附属中山市中医院妇产科,广东中山528400

出　　处：《中国当代医药》2023年第9期90-93,共4页China Modern Medicine

基　　金：广东省中医药局科研项目(20211417)。

摘　　要：目的 分析单胎足月妊娠晚期宫颈不成熟的影响因素。方法 回顾性选取2018年1月至2019年12月于中山市中医院妇产科就诊的单胎足月妊娠晚期孕妇的病例资料,共548份,按照孕妇宫颈是否成熟分为宫颈成熟组(252例)与宫颈不成熟组(296例)。收集并记录两组孕妇的年龄、孕前体重指数(BMI)及孕期增重、日常运动量、孕晚期阴道炎、宫颈物理治疗史、不良妊娠史及产次等个人信息,对其进行单因素分析,并对其中有统计学意义的因素进行多因素logistic回归分析。结果 单因素分析结果显示,宫颈不成熟与年龄大、孕前BMI指数高、日常运动量少、孕晚期阴道炎、既往有宫颈物理治疗史、无阴道分娩史相关,差异有统计学意义(P<0.05)。logistic回归分析结果显示年龄≥35岁(β=0.713,OR=2.040,95%CI=1.229~3.452)、孕前BMI≥24kg/m2(β=0.907,OR=2.684,95%CI=1.481~4.864)、日常缺乏运动量(β=1.715,OR=5.595,95%CI=2.582~11.954)、孕晚期阴道炎(β=0.993,OR=2.743,95%CI=1.488~4.896)、宫颈物理治疗史(β=1.013,OR=2.653,95%CI=1.365~4.803)、无阴道分娩史(β=1.823,OR=6.190,95%CI=2.791~13.508)是宫颈不成熟的独立危险因素(P<0.05)。结论 年龄≥35岁、孕前BMI≥24 kg/m2,日常缺乏运动量、孕晚期有阴道炎、既往有宫颈物理治疗史、无阴道分娩史是影响妊娠晚期宫颈成熟度的高危因素,为预防宫颈不成熟所带来的分娩并发症提供了临床参考依据。Objective To analyze the influencing factors of cervical immaturity in the third trimester of single term pregnancy.Methods A total of 548 pregnant women in the third trimester of full term pregnancy who visited the Department of Obstetrics and Gynecology of Zhongshan Hospital of Traditional Chinese Medicine from January 2018 to December 2019 were retrospectively selected.They were divided into cervical maturity group(252 cases)and cervical immaturity group(296 cases)according to whether the pregnant women had cervical maturity.The personal information of pregnant women in the two groups including age,pre-pregnancy body mass index(BMI),pregnancy weight gain,daily exercise,late pregnancy vaginitis,history of cervical physical therapy,history of adverse pregnancy and birth grade were collected and recorded.Univariate analysis was conducted,and statistically significant factors were analyzed by multivariate logistic regression.Results Univariate analysis showed that cervical immaturity was correlated with older age,higher BMI index before pregnancy,less daily exercise,vaginitis in late pregnancy,previous history of cervical physical therapy and no history of vaginal delivery,with statistical significances(P<0.05).Logistic regression analysis showed that age≥35 years(β=0.713,OR=2.040,95%CI=1.229-3.452),pre-pregnancy BMI≥24 kg/m2(β=0.907,OR=2.684,95%CI=1.481-4.864),daily lack of physical activity(β=1.715,OR=5.595,95%CI=2.582-11.954),vaginitis in the third trimester(β=0.993,OR=2.743,95%CI=1.488-4.896),history of cervical physical therapy(β=1.013,OR=2.653,95%CI=1.365-4.803),no history of vaginal delivery(β=1.823,OR=6.190,95%CI=2.791-13.508)was independent risk factors for cervical immaturity(P<0.05).Conclusion Age≥35 years,pre-pregnancy BMI≥24 kg/m2,lack of daily exercise,vaginitis in late pregnancy,previous history of cervical physical therapy,and no history of vaginal delivery were the high-risk factors affecting cervical maturity in late pregnancy,which provided clinical reference for the prevention of

关 键 词：单胎足月妊娠 妊娠晚期 宫颈不成熟 因素分析 

分 类 号：R719.3[医药卫生—妇产科学]