拉贝洛尔、硫酸镁、硝苯地平组合疗法优化妊娠高血压的妊娠结局的体会  

Experience of combination therapy of Iabetalol,magnesium sulfate and nifedipine in optimizing pregnancy outcome of pregnancy induced hypertension

作　　者：李咏梅 LI Yong-mei(Department of Obstetrics and Gynecology,Yibin Sixth People's Hospital,Yibin 644600,China)

机构地区：[1]宜宾市第六人民医院妇产科,四川宜宾644600

出　　处：《中国国境卫生检疫杂志》2022年第S01期152-154,共3页Chinese Journal of Frontier Health and Quarantine

摘　　要：目的观察拉贝洛尔、硫酸镁、硝苯地平组合疗法对妊娠高血压患者的治疗效果。方法本次研究对象均来自2020年11月-2022年1月在我院进行治疗的148例妊娠高血压患者,根据治疗方法的差异将所有患者平均分为两组,其中对照组74例患者均予以硝苯地平联合硫酸镁治疗,观察组74例患者则在对照组基础上联合拉贝洛尔治疗.对比分析两组患者的治疗效果。结果在接受了治疗干预之后,观察组患者的收缩压、舒张压全部都明显要低于常规组(P<0.05);在治疗干预之后观察组患者的不良妊娠结局发生率为8.10%,剖宫产率为25.67%,对照组患者的不良人生结局发生率为21.62%,剖宫产率为60.81%,观察组患者的不良妊娠结局发生率以及剖宫产率均显著低于对照组患者(P<0.05)。结论针对妊娠高血压患者采用拉贝洛尔、硫酸镁、硝苯地平组合疗法效果显著,可以有效的控制患者的血压指标,降低其不良妊娠结局发生率和剖宫产率,值得临床推广应用。Objective To observe the therapeutic effect of labetalol,magnesium sulfate and nifedipine on patients with pregnancy induced hypertension.Methods The subjects of this study were 148 patients with pregnancy induced hypertension who were treated in our hospital from November 2020 to Januaiy 2022.According to the differences in treatment methods,all patients were divided into two groups.74 patients in the control group were treated with nifedipine combined with magnesium sulfate,and 74 patients in the observation group were treated with labetalol on the basis of the control group.The treatment effects of the two groups were compared and analyzed.Results After the treatment intervention,the systolic and diastolic blood pressure of the observation group were significantly lower than that of the conventional group(p<0.05).After the treatment intervention,the incidence of adverse pregnancy outcome and cesarean section rate in the observation group were 8.10%,25.67%,21.62%and 60.81%respectively.The incidence of adverse pregnancy outcome and cesarean section rate in the observation group were significantly lower than those in the control group(p<0.05).Conclusion The combination therapy of labetalol,magnesium sulfate and nifedipine is effective for patients with pregnancy induced hypertension,which can effectively control the blood pressure index of patients,reduce the incidence of adverse pregnancy outcomes and cesarean section rate,and is worthy of clinical application.

关 键 词：拉贝洛尔 硫酸镁 硝苯地平 组合疗法 妊娠高血压 

分 类 号：R183[医药卫生—流行病学]