糖尿病肾病与非糖尿病肾病维持性血液透析患者的临床相关指标比较  

Comparison of clinical indicators between diabetic nephropathy and non-diabetic nephropathy patients undergoing maintenance hemodialysis

作　　者：潘金英[1] 陈友明[1] PAN Jinying;CHEN Youming(Department of Hemopurification,Fujian Provincial Hospital,Fujian Province,Fuzhou350001,China)

机构地区：[1]福建省立医院血液净化科,福建福州350001

出　　处：《中国当代医药》2023年第10期129-133,共5页China Modern Medicine

摘　　要：目的比较糖尿病肾病(DN)与非糖尿病肾病(NDN)维持性血液透析患者的临床相关指标。方法回顾性分析2021年6月至2022年6月福建省立医院收治的55例维持性血液透析患者的临床资料,根据原发疾病种类将其分为DN组26例和NDN组29例,比较两组患者的贫血、炎症反应、营养不良、钙磷代谢紊乱及心血管损伤的临床指标情况。结果DN组与NDN组的尿素氮、尿酸、红细胞计数、血清铁、C反应蛋白、白细胞计数、钙、磷水平比较,差异无统计学意义(P>0.05);DN组患者的肌酐、血红蛋白、血清白蛋白、前白蛋白、甲状旁腺素水平均低于NDN组,差异有统计学意义(P<0.05)。DN组患者的射血分数低于NDN组,差异有统计学意义(P<0.05)。DN组患者的左心室质量指数高于NDN组,差异有统计学意义(P<0.05)。两组患者左心室质量比较,差异无统计学意义(P>0.05)。结论DN患者较NDN患者更早进入维持性透析治疗,且其贫血、营养不良、心血管损伤情况更为严重。Objective To compare the clinically relevant indexes of diabetic nephropathy(DN)and non-diabetic nephropathy(NDN)maintenance hemodialysis patients.Methods The clinical data of 55 maintenance hemodialysis patients admitted to Fujian Provincial Hospital from June 2021 to June 2022 were retrospectively analyzed.According to the type of primary disease,the patients were divided into 26 patients in the DN group and 29 patients in the NDN group.The clinical indicators of anemia,inflammation,malnutrition,calcium and phosphorus metabolism disorders,and cardiovascular damage were compared between the two groups.Results There were no significant differences in urea nitrogen,uric acid,red blood cell count,serum iron,C-reactive protein,white blood cell count,calcium and phosphorus between DN group and NDN group(P>0.05).The creatinine,hemoglobin,albumin,prealbumin,parathyroid hormone of DN group were lower than those in NDN group,and the differences were statistically significant(P<0.05).The left ventricular ejection fraction of DN group was lower than that in NDN group,and the difference was statistically significant(P<0.05).The left ventricular mass index of DN group was higher than that in NDN group,and the difference was statistically significant(P<0.05).There was no significant difference in left ventricular mass between the two groups(P>0.05).Conclusion Patients with DN receive dialysis earlier than patients with NDN,and they had more severe anemia,malnutrition,and cardiovascular damage.

关 键 词：糖尿病肾病 血液透析 非糖尿病肾病 并发症 

分 类 号：R692.5[医药卫生—泌尿科学]