基于眼组织结构的死亡时间推断研究进展  

Research Progress on Estimation of Postmortem Interval Based on Ocular Tis⁃sues Structure

作　　者：吴慧 刘芳芳 伍俊达 谢英[1] WU Hui;LIU Fang-fang;WU Jun-da;XIE Ying(Department of Forensic Medicine,North Sichuan Medical College,Nanchong 637000,Sichuan Prov-ince,China;The Second People’s Hospital of Yibin,Yibin 644000,Sichuan Province,China;Xu-zhou District Branch of Yibin City Pubic Security Bureau,Yibin 644000,Sichuan Province,China)

机构地区：[1]川北医学院法医学系,四川南充637000 [2]宜宾市第二人民医院,四川宜宾644000 [3]宜宾市公安局叙州区分局,四川宜宾644000

出　　处：《法医学杂志》2023年第1期50-56,65,共8页Journal of Forensic Medicine

基　　金：四川省基层卫生事业发展研究中心资助项目(SWFZ17-Z-12);四川省教育厅基金资助项目(15ZA0215);南充市市校合作科研专项资助项目(19SXHZ0197)。

摘　　要：死亡时间(postmortem interval,PMI)推断是法医病理学研究的重点与热点问题。近年来,国内外学者利用眼组织推断PMI取得了一定进展,机体死后眼角膜、房水、虹膜、晶状体、玻璃体液、视网膜等改变均呈现与PMI高度相关的时序性变化规律。本文基于眼组织不同结构死后形态学、生物化学、分子学、遗传物质改变等方面,对PMI推断研究进展进行了综述,对存在的问题及发展趋势进行探讨。Estimation of postmortem interval(PMI)is one of the important research contents in forensic pathology,and it has always been the focus and hot spot of research work.In recent years,scholars at home and abroad have made some research progress in estimating PMI by using ocular tissue.After death,the changes of cornea,aqueous humor,iris,lens,vitreous humor and retina all show time sequence change rule highly related to PMI.This paper reviews the research progress of PMI estimation based on the morphological,biochemical,molecular and genetic material changes of different ocular tissue structures after death,and discusses the existing problems and development trends.

关 键 词：法医病理学 死亡时间 眼组织 角膜 玻璃体液 综述 

分 类 号：DF795.1[医药卫生—法医学]