精子特定形态学与部分精子动力学参数的相关性研究  

Study on the correlation between sperm specific morphology and some sperm kinetic parameters

作　　者：赖昱全 孙瑜冲 黄仔冠 范一鸣 沙合热扎提·衣里哈木 刘翛然[2] LAI Yuquan;SUN Yuchong;HUANG Ziguan;FAN Yiming;SHAHEREZATI Yilihamu;LIU Xiaoran(Xinjiang Medical University,Urumqi,Xinjiang 830054,China;Reproductive Medicine Center,First Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang 830054,China)

机构地区：[1]新疆医科大学,乌鲁木齐830054 [2]新疆医科大学附属第一院生殖医学中心,乌鲁木齐830054

出　　处：《重庆医学》2023年第7期1000-1003,1008,共5页Chongqing medicine

基　　金：新疆维吾尔自治区自然科学基金面上项目(2021D01C297);新疆医科大学大学生科研训练计划(cx2021067)。

摘　　要：目的探讨精子形态和部分精子动力学参数的相关性,分析精子的各种形态缺陷与各精子动力学参数间的相关性。方法采集2233份精液标本,进行精液常规检测和精子形态学分析,对异常精子的形态缺陷和精子动力学参数进行相关性分析。结果精子正常形态率与精子动力学参数均呈正相关性(P<0.05);精子头部畸形率(除精子浓度、非向前运动精子百分比)、中段畸形率、主段畸形率、过量残留胞浆精子率(除非向前运动精子百分比)与精子动力学参数均呈负相关性(P<0.05)。精子浓度与精子正常形态率呈线性相关(P<0.05);前向运动精子百分比与精子正常形态率、中段畸形率、主段畸形率、过量残留胞浆精子率呈线性相关(P<0.05);非前向运动精子百分比与精子中段畸形率呈线性相关(P<0.05);精子总活力与精子正常形态率、中段畸形率、主段畸形率、过量残留胞浆精子率均呈线性相关(P<0.05)。结论精子形态学与精子动力学参数间存在一定相关性,部分参数间呈线性相关。精子形态学检测与动力学参数检测相结合可以更好地评估精子质量。Objective To explore the correlation between sperm morphology and some sperm kinetic parameters,and analyze the correlation between sperm morphology defects and sperm kinetic parameters.Methods A total of 2233 semen samples were collected for routine semen test and sperm morphological analysis,and the correlation between the morphological structure defects of abnormal sperm and sperm kinetic parameters was analyzed.Results There was a positive correlation between normal sperm morphology rate and sperm kinetic parameters(P<0.05).The sperm head deformity rate(except for percentage of non-forward-moving sperm),middle segment deformity rate,main segment deformity rate,excessive residual cytoplasmic sperm rate were negatively correlated with sperm dynamics parameters(except for percentage of non-forward-moving sperm),P<0.05.There was a linear correlation between sperm concentration and normal sperm morphology rate(P<0.05).The percentage of forward-moving sperm was linearly correlated with normal sperm morphology rate,middle segment deformity rate,main segment deformity rate and excessive residual cytoplasmic sperm rate(P<0.05).There was a linear correlation between the percentage of non-forward-moving sperm and the of sperm middle segment deformity rate(P<0.05).The total sperm activity was linearly correlated with normal sperm morphology rate,middle segment deformity rate,main segment deformity rate and excessive residual cytoplasmic sperm(P<0.05).Conclusion There is a certain correlation between sperm morphology and sperm kinetic parameters,and some parameters are linear correlation.Combined detection of sperm morphology and sperm kinetic parameters can evaluate sperm quality better.

关 键 词：精子形态 精子动力学参数 前向运动精子 精子浓度 精子畸形 

分 类 号：R446.9[医药卫生—诊断学]