K_(2)CO_(3)辅助钯催化C-H活化反应的理论研究  

Theoretical Study on K_(2)CO_(3)-Assisted Pd-catalyzed C-H Activation Reaction

作　　者：白文己 石宇冰 李江平 于嘉玮 母伟花[1] BAI Wen-ji;SHI Yu-bing;LI Jiang-ping;YU Jia-wei;MU Wei-hua(School of Chemistry and Chemical Engineering,Yunnan Normal University,Yunnan Kunming 650500,China)

机构地区：[1]云南师范大学化学化工学院,云南昆明650500

出　　处：《广州化工》2023年第2期6-12,24,共8页GuangZhou Chemical Industry

基　　金：国家自然科学基金(No:21763033);云南省万人计划“青年拔尖人才”专项资助项目。

摘　　要：K_(2)CO_(3)是一种常见的碱金属碳酸盐,在有机合成中常被用作碱性添加剂,以加快过渡金属尤其是钯催化C-H活化反应的速率或提高反应产率。因此,研究K_(2)CO_(3)辅助的钯催化C-H活化反应成为近年来有机合成和理论计算领域的热点之一。本文对近十年来K_(2)CO_(3)辅助钯催化C-H活化反应的最新理论研究进展进行分类总结,重点对钯催化C-H活化反应的微观机理、K_(2)CO_(3)的作用机制等进行了深入探讨,并对该领域的发展前景进行展望。As a common alkali metal carbonate,K_(2)CO_(3) is often used as a basic additive in organic synthesis to accelerate reaction rate or improve yield of transitionmetal especially palladium-catalyzed C-H activation reaction.Consequently,K_(2)CO_(3)-assistedpalladium-catalyzed C-H activation reaction has attracted extensive attention from researchers in both organic synthesis and theoretical study areasin recent years.Herein,the latest theoretical research progress on K_(2)CO_(3)-assisted palladium-catalyzed C-H activation reactions was summarized,corresponding computational results about microcosmic reaction mechanism and role of K_(2)CO_(3) additive were emphasized.The prospects of future development in this field were also forecasted.

关 键 词：K_(2)CO_(3) C-H活化 钯催化 反应机理 反应选择性 

分 类 号：O643.12[理学—物理化学]