Fractional flow reserve and non-hyperemic indices:Essential tools for percutaneous coronary interventions  

作　　者：Amine Mamoun Boutaleb Chadi Ghafari Claudiu Ungureanu Stéphane Carlier 

机构地区：[1]Department of Cardiology,Ibn Rochd University Hospital,Casablanca 20230,Casablanca,Morocco [2]Department of Cardiology,Centre Hospitalier Universitaire Ambroise Paré,Mons 7000,Belgium [3]Department of Cardiology,University of Mons,Mons 7000,Belgium [4]Catheterization Unit,Jolimont Hospital,La Louvière 7100,Belgium,Belgium

出　　处：《World Journal of Clinical Cases》2023年第10期2123-2139,共17页世界临床病例杂志

摘　　要：Hemodynamical evaluation of a coronary artery lesion is an important diagnostic step to assess its functional impact.Fractional flow reserve(FFR)received a class IA recommendation from the European Society of Cardiology for the assessment of angiographically moderate stenosis.FFR evaluation of coronary artery disease offers improvement of the therapeutic strategy,deferring unnecessary procedures for lesions with a FFR>0.8,improving patients'management and clinical outcome.Post intervention,an optimal FFR>0.9 post stenting should be reached and>0.8 post drug eluting balloons.Non-hyperemic pressure ratio measurements have been validated in previous studies with a common threshold of 0.89.They might overestimate the hemodynamic significance of some lesions but remain useful whenever hyperemic agents are contraindicated.FFR remains the gold standard reference for invasive assessment of ischemia.We illustrate this review with two cases introducing the possibility to estimate also non-invasively FFR from reconstructed 3-D angiograms by quantitative flow ratio.We conclude introducing a hybrid approach to intermediate lesions(DFR 0.85-0.95)potentially maximizing clinical decision from all measurements.

关 键 词：Fractional flow measurements Coronary artery physiology Quantitative flow reserve Non-hyperemic pressure ratios 

分 类 号：R541.4[医药卫生—心血管疾病]